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[墨西哥城耳式血氧仪Biox-III的准确性及其对碳氧血红蛋白的敏感性]

[Accuracy of an the ear oximeter Biox-III and its sensitivity to carboxyhemoglobin in Mexico City].

作者信息

Pérez-Padilla J R, Bracamonte-Peraza R, Manrique G, Ruiz-Primo M E

出版信息

Arch Inst Cardiol Mex. 1986 Jul-Aug;56(4):303-7.

PMID:2945522
Abstract

Ear oximeters estimate arterial oxygen saturation (Sa02) measuring the characteristics of light transmission through the ear lobe. We tested the accuracy of a new ear oximeter (Biox-III) in Mexico City comparing its estimates (Sa02OXI) with Sa02 measured by a Co-Oximeter, in a simultaneously taken arterial blood sample. We used two indexes in the arterial sample: Sa02 of the total hemoglobin (Sa02T) given directly by the Co-Oximeter and Sa02 of the hemoglobin available for oxygenation (Sa02A) which corrects for the presence of carboxyhemoglobin and metahemoglobin. We studied 21 subjects with a total of 100 simultaneous samples with a Sa02T ranging from 36.2% to 97.2%. The samples were obtained with the subjects resting, during light exercise, during rebreathing and increasing the Fi02. Spearman and Pearson's correlation coefficients between Sa02OXI and Sa02A were 0.97, and between Sa02OXI and Sa02T were 0.96. Lineal regression equations were: Sa02T = 2.047 (Sa02OXI) -8.5 and Sa02A = 1.102 (Sa02OXI) -9.32. Slopes of the equations and correlation coefficients were statistically significant (P less than 0.001). Mean error of Sa02OXI compared with Sa02T (Sa02T-Sa02OXI) was -4.4% and compared with Sa02A (Sa02A-Sa02OXI) was -0.4%, with a standard deviation of 3.4% and 3.5% respectively. In the presence of carboxyhemoglobin the ear oximeter overestimates Sa02T but not Sa02A. Measurement error increases during rebreathing maybe because error increases at low Sa02 and because of the delay in oximeter's response in a situation of a continuously falling Sa02. Ear oximeter Biox-III estimates Sa02 in Mexico City as accurately as the Biox-IIA at sea level. Sa02 measurement is quick, easy, continuous and non-invasive, which increase its potential clinical and research application.

摘要

耳部血氧计通过测量透过耳垂的光传输特性来估算动脉血氧饱和度(SaO₂)。我们在墨西哥城测试了一种新型耳部血氧计(Biox-III)的准确性,将其估算值(SaO₂OXI)与通过同时采集的动脉血样用共血氧计测量的SaO₂进行比较。我们在动脉血样中使用了两个指标:共血氧计直接给出的总血红蛋白的SaO₂(SaO₂T)以及可用于氧合的血红蛋白的SaO₂(SaO₂A),后者校正了碳氧血红蛋白和高铁血红蛋白的存在。我们研究了21名受试者,共获得100组同时采集的样本,SaO₂T范围为36.2%至97.2%。样本是在受试者休息、轻度运动、重复呼吸以及增加吸入氧分数(FiO₂)期间采集的。SaO₂OXI与SaO₂A之间的斯皮尔曼和皮尔逊相关系数为0.97,SaO₂OXI与SaO₂T之间的相关系数为0.96。线性回归方程为:SaO₂T = 2.047(SaO₂OXI) - 8.5,SaO₂A = 1.102(SaO₂OXI) - 9.32。方程的斜率和相关系数具有统计学意义(P小于0.001)。与SaO₂T(SaO₂T - SaO₂OXI)相比,SaO₂OXI的平均误差为 - 4.4%,与SaO₂A(SaO₂A - SaO₂OXI)相比为 - 0.4%,标准差分别为3.4%和3.5%。在存在碳氧血红蛋白的情况下,耳部血氧计高估了SaO₂T,但没有高估SaO₂A。重复呼吸期间测量误差增加,可能是因为在低SaO₂时误差增加,以及在SaO₂持续下降的情况下血氧计响应存在延迟。在墨西哥城,耳部血氧计Biox-III估算SaO₂的准确性与海平面的Biox-IIA相当。SaO₂测量快速、简便、连续且无创,这增加了其在临床和研究中的潜在应用。

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