Ishikawa Hayato, Shiomi Shinya
Kumamoto University, Kumamoto, Japan.
Kumamoto University, Kumamoto, Japan.
Alkaloids Chem Biol. 2018;79:1-70. doi: 10.1016/bs.alkal.2017.12.001. Epub 2018 Feb 1.
This chapter covers the literature since the advent, in the 21st century, of total syntheses of alkaloids using enantio- or diastereoselective organocatalytic reactions to construct the alkaloid scaffolds. The details of these alkaloid syntheses are described separately for each basic skeleton, including indole, indoline, oxindole, and piperidine alkaloids.
本章涵盖了自21世纪以来,利用对映选择性或非对映选择性有机催化反应构建生物碱骨架来进行生物碱全合成的相关文献。这些生物碱合成的细节针对每个基本骨架分别进行描述,包括吲哚、二氢吲哚、氧化吲哚和哌啶生物碱。