Vilmann A, Vilmann P, Vilmann H
Br J Oral Maxillofac Surg. 1986 Oct;24(5):376-82. doi: 10.1016/0266-4356(86)90023-9.
A consecutive series of 43 pyogenic granulomata in the oral cavity is presented. Most were located to the marginal vestibular gingivae and only a minority (12%) of these had a history of trauma whereas 70% in extragingival locations had a previous history of injury. On the basis of an evaluation of oral conditions the aetiology and the pathogenesis of the pyogenic granuloma are discussed. Trauma, microtrauma due to toothbrushing and gingival inflammation seem to be pathogenetic elements. It is suggested that the granuloma is a localised tissue response to a non-specific irritant.
本文报告了口腔内连续的43例化脓性肉芽肿病例。大多数位于边缘前庭龈,其中只有少数(12%)有创伤史,而龈外部位的70%有既往损伤史。基于对口腔状况的评估,讨论了化脓性肉芽肿的病因和发病机制。创伤、刷牙引起的微创伤和牙龈炎症似乎是致病因素。有人认为肉芽肿是对非特异性刺激物的局部组织反应。