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无移位舟状骨骨折治疗偏好的联合分析

Conjoint Analysis of Treatment Preferences for Nondisplaced Scaphoid Fractures.

作者信息

Shammas Ronnie L, Mela Nathan, Wallace Scott, Tong Betty C, Huber Joel, Mithani Suhail K

机构信息

Duke University School of Medicine, Durham, NC.

Fuqua School of Business, Duke University, Durham, NC.

出版信息

J Hand Surg Am. 2018 Jul;43(7):678.e1-678.e9. doi: 10.1016/j.jhsa.2017.12.021. Epub 2018 Feb 15.

Abstract

PURPOSE

We used conjoint analysis to assess the relative importance of factors that influence a patient's decision between surgical or nonsurgical management of a nondisplaced scaphoid fracture. Our hypothesis was that out-of-pocket costs will have a greater influence on decision making than the time spent in a cast or brace, degree of soreness, or the risk of treatment failure.

METHODS

Two-hundred and fifty participants were recruited using Amazon Mechanical Turk and asked to assume that they had experienced a nondisplaced scaphoid waist fracture. They then indicated their relative preferences among 13 pairs of alternatives with variations in the following attributes: time in a cast, time in a brace, duration of ongoing soreness, risk of treatment failure (by which we meant scaphoid nonunion), out-of-pocket costs based on estimates of direct costs ($500-2,500), and apprehension about surgery. A conjoint analysis was used to determine the relative importance of these factors when choosing between surgical or nonsurgical management.

RESULTS

The factor with the greatest influence on treatment choice was the cost of the procedure. After assessing the respondent's apprehension to undergo surgery, a sensitivity analysis showed the proportion of respondents who would choose surgery given different outcomes. To make the predicted share of those who are "not worried" about surgery equal to those who are "somewhat worried" or "a little worried" would require that the cost of surgery increase by $2,700. In addition, 2 weeks in a cast, 3 weeks in a brace, 2 months of soreness, or a 2% increase in the risk of fracture nonunion generates the same surgical choice probability as a $2,000 increase in the out-of-pocket cost of surgery.

CONCLUSIONS

As conceptualized in this conjoint analysis, out-of-pocket costs and apprehension about surgery seem to have a greater impact on a decision for surgery than the time spent in a brace or cast and the risk of treatment failure.

TYPE OF STUDY/LEVEL OF EVIDENCE: Economic and decision analysis III.

摘要

目的

我们运用联合分析来评估影响患者在无移位舟状骨骨折的手术或非手术治疗之间做出决策的因素的相对重要性。我们的假设是,自付费用对决策的影响将大于打石膏或佩戴支具的时间、疼痛程度或治疗失败的风险。

方法

通过亚马逊土耳其机器人招募了250名参与者,并要求他们假设自己经历了无移位的舟状骨腰部骨折。然后,他们在13对备选方案中表明了自己的相对偏好,这些备选方案在以下属性上有所不同:打石膏的时间、佩戴支具的时间、持续疼痛的持续时间、治疗失败的风险(我们指的是舟状骨不愈合)、基于直接费用估计的自付费用(500 - 2500美元)以及对手术的担忧。使用联合分析来确定在手术或非手术治疗之间进行选择时这些因素的相对重要性。

结果

对治疗选择影响最大的因素是手术费用。在评估了受访者对手术的担忧之后,敏感性分析显示了在不同结果下会选择手术的受访者比例。要使“不担心”手术的受访者预测比例与“有些担心”或“有点担心”的受访者比例相等,手术费用需要增加2700美元。此外,打2周石膏、佩戴3周支具、疼痛2个月或骨折不愈合风险增加2%所产生的手术选择概率与手术自付费用增加2000美元相同。

结论

正如本联合分析中所概念化的那样,自付费用和对手术的担忧似乎比佩戴支具或打石膏的时间以及治疗失败的风险对手术决策的影响更大。

研究类型/证据水平:经济与决策分析III级。

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