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来自山羊乳腺炎的微生物病原体及金黄色葡萄球菌分离株的噬菌体分型

Microbial pathogens from goat mastitis and phage-typing of Staphylococcus aureus isolates.

作者信息

Al-Graibawi M A, Sharma V K, Al-Shammari A J

出版信息

Comp Immunol Microbiol Infect Dis. 1986;9(1):23-8. doi: 10.1016/0147-9571(86)90071-8.

DOI:10.1016/0147-9571(86)90071-8
PMID:2945693
Abstract

Examination of milk from goats yielded 41 strains from 40 clinically affected halves; 15 were Staphylococcus aureus, 6 Staph. epidermis, 1 Streptococcus agalactiae, 2 Strept. dysgalactiae, 5 Strept. uberis, 2 Corynebacterium pyogenes, 3 Escherichia coli, 3 Pasteurella spp. and 4 Mycoplasma spp. One half had dual infection of Staph. aureus and Strept. dysgalactiae. Twenty two of the 297 milk samples from apparently normal halves also harboured pathogens comprising of 9 Staph. aureus, 1 Strept. agalactiae, 2 E. coli, 2 Pasteurella spp., 2 Candida albicans and 6 Mycoplasma spp. Most of the bacterial isolates were sensitive to many broad spectrum antibiotics. Twenty of the 24 Staph. aureus isolates were phase typable by a set of 23 human Staphylococcal International Phages suggesting the utility of these phages for the typing of goat strains. The isolates were grouped into 15 phage-types, many of which have been reported from human infections in Iraq. This indicates the possibility of association of human strains of Staph. aureus in caprine mastitis. No definite correlation could be noted between antibiogram and phage types of Staph. aureus strains.

摘要

对山羊奶进行检测,从40个临床感染的乳房中分离出41株菌株;其中15株为金黄色葡萄球菌,6株为表皮葡萄球菌,1株为无乳链球菌,2株为停乳链球菌,5株为乳房链球菌,2株为化脓棒状杆菌,3株为大肠杆菌,3株为巴氏杆菌属,4株为支原体属。有一个乳房同时感染了金黄色葡萄球菌和停乳链球菌。在来自外观正常乳房的297份奶样中,有22份也含有病原体,包括9株金黄色葡萄球菌、1株无乳链球菌、2株大肠杆菌、2株巴氏杆菌属、2株白色念珠菌和6株支原体属。大多数细菌分离株对多种广谱抗生素敏感。24株金黄色葡萄球菌分离株中有20株可被一组23种人源葡萄球菌国际噬菌体进行噬菌体分型,这表明这些噬菌体可用于山羊菌株的分型。这些分离株被分为15个噬菌体类型,其中许多在伊拉克的人类感染中已有报道。这表明在山羊乳腺炎中存在人源金黄色葡萄球菌菌株的关联可能性。金黄色葡萄球菌菌株的抗菌谱与噬菌体类型之间未发现明确的相关性。

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