Sabouri Masih, Mahabadi Amir, Tabesh Homayoun, Rezvani Majeed, Kouchekzadeh Masih, Namazi Ali
Department of Neurosurgery, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2018 Jan 22;7:6. doi: 10.4103/abr.abr_77_15. eCollection 2018.
Cerebral aneurysms are a kind of cardiovascular diseases which are accompanied with high morbidity and mortality due to rupturing and causing subarachnoid hemorrhages. The current study aimed to determine epidemiologic and demographic features and prognosis of patients with cerebral aneurysms.
In this cross-sectional study, 465 patients with cerebral aneurysms hospitalized in Al-Zahra Hospital were studied. The required information including demographic, epidemiologic, and clinical features of the disease were extracted from their records. The obtained data were analyzed using SPSS software and the factors associated with the prognosis of the disease were determined.
Four hundred and sixty-five cases with cerebral aneurysm undergoing surgery were investigated. The mean age of the patients was 48 ± 14 years whereas 216 cases (46.5%) were male and 249 (53.5%) were female. Two hundred and thirty-seven patients (51%) remitted completely while the disease caused moderate disability in 84 cases (18.1%), severe disability in 24 ones (5.2%) and vegetative state in 9 cases (1.9%) and mortality in 57 ones while it was unknown in 54 cases (11.6%). In terms of the age of patient, WFNS index, anatomical position of aneurysm, type of aneurysm lesion, the incidence season of the disease, type of postoperative complications, family history and operative approach, the disease outcome had a significant difference while gender, ethnicity, and risk factors had no significant effect on the disease outcome.
According to the type of aneurysm, the incidence position of the aneurysm and other epidemiologic, demographic, and clinical features, providing the prevention and treatment strategies is necessary.
脑动脉瘤是一种心血管疾病，因其破裂导致蛛网膜下腔出血，发病率和死亡率都很高。本研究旨在确定脑动脉瘤患者的流行病学和人口统计学特征以及预后情况。
在这项横断面研究中，对在阿尔-扎赫拉医院住院的465例脑动脉瘤患者进行了研究。从他们的病历中提取了包括疾病的人口统计学、流行病学和临床特征等所需信息。使用SPSS软件对获得的数据进行分析，并确定与疾病预后相关的因素。
对465例接受手术的脑动脉瘤病例进行了调查。患者的平均年龄为48±14岁，其中男性216例（46.5%），女性249例（53.5%）。237例患者（51%）完全缓解，84例（18.1%）出现中度残疾，24例（5.2%）出现重度残疾，9例（1.9%）处于植物人状态，57例死亡，54例（11.6%）情况不明。在患者年龄、WFNS指数、动脉瘤的解剖位置、动脉瘤病变类型、疾病发病季节、术后并发症类型、家族史和手术方式方面，疾病结局有显著差异，而性别、种族和危险因素对疾病结局无显著影响。
根据动脉瘤类型、动脉瘤发病位置以及其他流行病学、人口统计学和临床特征，制定预防和治疗策略很有必要。
