Sharma B S, Sinha Sumit, Mehta V S, Suri A, Gupta Aditya, Mahapatra A K
Department of Neurosurgery, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi 110029, India.
Childs Nerv Syst. 2007 Mar;23(3):327-33. doi: 10.1007/s00381-006-0253-x. Epub 2006 Nov 21.
Intracranial aneurysms are rare in children and have different epidemiological, clinical, and morphological characteristics and outcome from those in adults.
We analyzed demographic, clinical, radiologic features, treatment, and outcome in 55 patients <18 years of age, treated from Jan 1995 through December 2005.
Intracranial aneurysms in children below 18 years constituted 4% of all intracranial aneurysms. Internal Carotid artery (ICA) bifurcation was the commonest location. About half of the aneurysms were complex. Three-fourth of the patients required surgical treatment. Two patients died, constituting 5% mortality. Two patients (5%) had poor outcome, whereas the majority (90%) had a favorable outcome.
Pediatric aneurysms have male predominance, higher incidence of clinical features of mass effect or seizures, high incidence of large, traumatic/mycotic aneurysms, associated illnesses and ICH/IVH and hydrocephalus, better Hunt and Hess grades at presentation, ICA bifurcation as the commonest site, and better outcome than their adult counterparts.
儿童颅内动脉瘤较为罕见,其流行病学、临床、形态学特征及预后与成人不同。
我们分析了1995年1月至2005年12月期间接受治疗的55例18岁以下患者的人口统计学、临床、放射学特征、治疗及预后情况。
18岁以下儿童颅内动脉瘤占所有颅内动脉瘤的4%。颈内动脉(ICA)分叉处是最常见的部位。约一半的动脉瘤为复杂型。四分之三的患者需要手术治疗。2例患者死亡,死亡率为5%。2例患者(5%)预后不良,而大多数患者(90%)预后良好。
儿童动脉瘤男性居多,占位效应或癫痫临床特征的发生率较高,大型、创伤性/霉菌性动脉瘤、相关疾病及脑出血/脑室出血和脑积水的发生率较高,就诊时Hunt和Hess分级较好,ICA分叉处是最常见部位,且预后优于成人患者。