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微生物风险评估鉴定框架。

A microbial identification framework for risk assessment.

机构信息

Biotechnology Section, New Substances Control and Assessment Bureau, Health Canada, Ottawa, Ontario, K1A 0K9, Canada.

Regulatory Science and Policy, Biotechnology Section, Emerging Priorities Division, Environment Canada, Gatineau, Québec K1A 0H3, Canada.

出版信息

Food Chem Toxicol. 2018 Jun;116(Pt A):60-65. doi: 10.1016/j.fct.2018.02.040. Epub 2018 Feb 16.

DOI:10.1016/j.fct.2018.02.040
PMID:29458165
Abstract

Micro-organisms are increasingly used in a variety of products for commercial uses, including cleaning products. Such microbial-based cleaning products (MBCP) are represented as a more environmentally-friendly alternative to chemically based cleaning products. The identity of the micro-organisms formulated into these products is often considered confidential business information and is not revealed or it is only partly revealed (i.e., identification to the genus, not to the species). That paucity of information complicates the evaluation of the risk associated with their use. The accurate taxonomic identification of those micro-organisms is important so that a suitable risk assessment of the products can be conducted. To alleviate difficulties associated with adequate identification of micro-organisms in MBCP and other products containing micro-organisms, a microbial identification framework for risk assessment (MIFRA) has been elaborated. It serves to provide guidance on a polyphasic tiered approach, combining the data obtained from the use of various methods (i.e., polyphasic approach) combined with the sequential selection of the methods (i.e., tiered) to achieve a satisfactory identity of the micro-organism to an acceptable taxonomic level. The MIFRA is suitable in various risk assessment contexts for micro-organisms used in any commercial product.

摘要

微生物被越来越多地应用于各种商业用途的产品中,包括清洁产品。这种基于微生物的清洁产品(MBCP)被认为是一种更环保的化学清洁产品替代品。这些产品中所使用的微生物的身份通常被视为商业机密信息,不会被透露或仅部分透露(即,只识别到属,而不是种)。这种信息的缺乏使得评估其使用相关风险变得复杂。准确的分类学鉴定对于进行适当的产品风险评估非常重要。为了缓解 MBCP 和其他含有微生物的产品中微生物充分鉴定的困难,已经制定了微生物风险评估鉴定框架(MIFRA)。它旨在提供多相分层方法的指导,结合使用各种方法(即多相方法)获得的数据,并结合方法的顺序选择(即分层),以达到对微生物的可接受分类学水平的满意鉴定。MIFRA 适用于各种风险评估情境,适用于任何商业产品中使用的微生物。

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