Ryzhov Anton, Bray Freddie, Ferlay Jacques, Fedorenko Zoya, Goulak Liudmyla, Gorokh Yevgeniy, Soumkina Olena, Znaor Ariana
National Cancer Registry of Ukraine, Ukrainian National Cancer Institute, Kyiv, Ukraine; Taras Shevchenko National University of Kyiv, Ukraine; Cancer Surveillance Section, International Agency for Research on Cancer, Lyon, France.
Cancer Surveillance Section, International Agency for Research on Cancer, Lyon, France.
Cancer Epidemiol. 2018 Apr;53:156-165. doi: 10.1016/j.canep.2018.02.002. Epub 2018 Feb 22.
Cancer notification has been mandatory in Ukraine since 1953, with the National Cancer Registry of Ukraine (NCRU) established in 1996. The aim of this study was to provide a comprehensive evaluation of the data quality at the NCRU.
Qualitative and semi-quantitative methods were used to assess the comparability, completeness, validity and timeliness of cancer incidence data from the NCRU for the period 2002-2012.
Cancer registration procedures at the NCRU are in accordance with international standards and recommendations. Semi-quantitative methods suggested the NCRU's data was reasonably complete, although decreases in age-specific incidence and mortality rates in the elderly indicated some missing cases at older ages. The proportion of microscopically-verified cases increased from 73.6% in 2002 to 82.3% in 2012, with death-certificate-only (DCO) proportions stable at around 0.1% and unknown stage recorded in 9.6% of male and 7.5% of female solid tumours. Timeliness was considered acceptable, with reporting >99% complete within a turn-around time of 15 months.
While timely reporting of national data reflects the advantages of a mandatory data collection system, a low DCO% and observed age-specific declines suggest possible underreporting of incidence and mortality data, particularly at older ages. Overall, the evaluation indicates that the data are reasonably comparable and thus may be used to describe the magnitude of the cancer burden in Ukraine. Given its central role in monitoring and evaluation of cancer control activities, ensuring the sustainability of NCRU operations throughout the process of healthcare system reform is of utmost importance.
自1953年起，乌克兰实行癌症通报制度，并于1996年设立了乌克兰国家癌症登记处（NCRU）。本研究旨在对NCRU的数据质量进行全面评估。
采用定性和半定量方法，评估NCRU在2002 - 2012年期间癌症发病率数据的可比性、完整性、有效性和及时性。
NCRU的癌症登记程序符合国际标准和建议。半定量方法表明，NCRU的数据较为完整，不过老年人年龄别发病率和死亡率的下降表明老年人群存在一些漏报病例。显微镜确诊病例的比例从2002年的73.6%增至2012年的82.3%，仅依据死亡证明（DCO）的比例稳定在0.1%左右，9.6%的男性实体瘤病例和7.5%的女性实体瘤病例记录为分期不明。及时性被认为是可接受的，在15个月的周转时间内报告完成率>99%。
虽然国家数据的及时报告体现了强制性数据收集系统的优势，但低DCO%以及观察到的年龄别下降表明发病率和死亡率数据可能存在漏报情况，尤其是在老年人群中。总体而言，评估表明这些数据具有合理的可比性，因此可用于描述乌克兰癌症负担的规模。鉴于其在癌症控制活动监测和评估中的核心作用，在医疗体系改革全过程中确保NCRU运作的可持续性至关重要。
