Tzukert A A, Leviner E, Sela M
Oral Surg Oral Med Oral Pathol. 1986 Oct;62(4):385-8. doi: 10.1016/0030-4220(86)90286-0.
Ninety patients (thirty-nine men, fifty-one women with a mean age of 45.4 years with rheumatic heart disease or prosthetic heart valves, were subjected to a total of 1617 dental procedures, which required about 3400 patient/dentist encounters. All treatments were performed according to the protocol described in the present article. Although theory expects three to six cases of infective endocarditis cases in the described population, none of the patients have encountered the disease (p = 0.0013). A conceptual approach, as well as the protocol, is presented. Properly applied, the protocol will reduce the probability of iatrogenic and self-inflicted bacteremia, thus elevating the efficacy of the preventive process.
90名患者（39名男性，51名女性，平均年龄45.4岁，患有风湿性心脏病或人工心脏瓣膜）共接受了1617次牙科治疗，这需要约3400次患者/牙医接触。所有治疗均按照本文所述方案进行。尽管理论上预计在所描述的人群中会有3至6例感染性心内膜炎病例，但没有一名患者患上该疾病（p = 0.0013）。本文介绍了一种概念性方法以及该方案。正确应用该方案将降低医源性和自身造成的菌血症的可能性，从而提高预防过程的效果。
