Al-Chalabi Najwa Jamil Abdulrazzak, Al-Quisi Ahmed Fadhil, Abdul Lateef Thair
Al-Shaheed Ghazi Al-Hariri Specialized Surgeries Teaching Hospital in Medical City, Ministry of Health.
Oral and Maxilloficial Department, Collage of Dentisty, Baghdad University, Baghdad, Iraq.
J Craniofac Surg. 2018 May;29(3):e267-e271. doi: 10.1097/SCS.0000000000004307.
This study was designed to evaluate the role of single session autologous facial fat grafting in correcting facial asymmetries after mixing it with platelet-rich fibrin (PRF) and injecting them into rich vascular facial muscular plane.
Fifteen patients (12 females and 3 males) with age ranging from 18 years to 40 years were included in this study and followed up during 6 months, all the patients were treated in the Al-Shaheed Ghazi Al-Hariri for specialized surgeries hospital (Medical City, Baghdad, Iraq).Autologous fat with PRF injected in facial muscular plane was the standardized method in the treatment of acquired and congenital facial defects.Results were evaluated by 2 plastic surgeons using visual analogue scale.Interexaminer and intraexaminer calibration of the visual analogue scale were carried out by using paired t test.
This prospective study showed that the majority of patients (73.3%) needed only a single session for creating a noticeable improvement in facial volumes and contours.
Mixing fat with PRF and injecting them by using facial autologous muscular injection technique offers better graft survival by utilizing the growth factors and cytokines in PRF clot together with rich vascular plexus in the muscular layer consequently.
本研究旨在评估单次自体面部脂肪移植与富血小板纤维蛋白（PRF）混合后注入面部富含血管的肌肉平面在矫正面部不对称中的作用。
本研究纳入了15例年龄在18岁至40岁之间的患者（12例女性和3例男性），并进行了6个月的随访，所有患者均在伊拉克巴格达医学城的烈士加齐·哈里里专科医院接受治疗。将自体脂肪与PRF注入面部肌肉平面是治疗后天性和先天性面部缺陷的标准化方法。由2名整形外科医生使用视觉模拟量表评估结果。通过配对t检验对视觉模拟量表进行检查者间和检查者内校准。
这项前瞻性研究表明，大多数患者（73.3%）仅需单次治疗就能在面部体积和轮廓上取得显著改善。
将脂肪与PRF混合并通过面部自体肌肉注射技术注入，利用PRF凝块中的生长因子和细胞因子以及肌肉层中丰富的血管丛，可提高移植脂肪的存活率。
