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难治性青光眼同一象限中失败的 Ahmed 青光眼引流阀置换为 Baerveldt 青光眼植入物的手术效果。

Surgical Outcome of Replacing a Failed Ahmed Glaucoma Valve by a Baerveldt Glaucoma Implant in the Same Quadrant in Refractory Glaucoma.

机构信息

Departments of Medicine.

Ophthalmology, Université de Montréal, University Ophthalmology Center, Maisonneuve-Rosemont Hospital, Maisonneuve-Rosemont Hospital Research Center, Montreal, QC, Canada.

出版信息

J Glaucoma. 2018 May;27(5):421-428. doi: 10.1097/IJG.0000000000000912.

Abstract

PURPOSE

The purpose of this study was to describe the surgical technique and outcomes in eyes that underwent surgery to replace a failed Ahmed valve by a Baerveldt glaucoma implant in the same quadrant.

METHODS

This study was a retrospective case series of 9 patients. Parameters analyzed include age, glaucoma type, prior surgery, complications, intraocular pressure (IOP), visual acuity, and number of glaucoma medications before and after the surgery. Surgical success was defined as having either an IOP below 21 mm Hg or a 20% IOP reduction, with or without hypotensive agent.

RESULTS

The mean follow-up duration was 47 months. After surgery, at the time of final follow-up, the mean IOP decreased from 29.9 mm Hg to 16.7 mm Hg (36% of mean IOP reduction; P=0.008). There was a significant reduction of hypotensive agents from a mean of 4.33 to 2.22 (P=0.02). The visual acuity did not have a significant deterioration (P=0.07). In the final visit, 5 of 9 patients met total success criteria and 2 patients were qualified successes. Two cases failed totally after 69 and 125 months of follow-up. The cumulative probability of total success after 6 months was 76% and this rate remained stable until the sixth year. One patient had bullous keratopathy. Two patients had early postoperative pressure spikes: the first patient was treated by trabeculectomy, and the second by vitrectomy.

CONCLUSIONS

A replacement of the failed Ahmed glaucoma valve by a new Baerveldt glaucoma implant in the same quadrant can be a reasonable choice to control refractory glaucoma.

摘要

目的

本研究旨在描述在同一象限内对失败的 Ahmed 青光眼引流阀进行手术替换为 Baerveldt 青光眼植入物的手术技术和结果。

方法

这是一项回顾性病例系列研究,共纳入 9 例患者。分析的参数包括年龄、青光眼类型、既往手术、并发症、眼内压(IOP)、视力和手术前后的降眼压药物数量。手术成功定义为 IOP 低于 21mmHg 或 IOP 降低 20%,同时或不使用降压药物。

结果

平均随访时间为 47 个月。手术后,在最终随访时,平均 IOP 从 29.9mmHg 降至 16.7mmHg(平均 IOP 降低 36%;P=0.008)。降压药物的使用量从平均 4.33 种显著减少至 2.22 种(P=0.02)。视力没有明显恶化(P=0.07)。在最终随访时,9 例患者中有 5 例符合总体成功标准,2 例为合格成功。2 例分别在 69 个月和 125 个月的随访后完全失败。术后 6 个月的总成功率累积概率为 76%,该比率一直稳定至第 6 年。1 例患者发生大泡性角膜病变。2 例患者术后早期眼压升高:第 1 例患者行小梁切除术治疗,第 2 例患者行玻璃体切除术治疗。

结论

在同一象限内用新的 Baerveldt 青光眼植入物替换失败的 Ahmed 青光眼引流阀可以是控制难治性青光眼的合理选择。

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