Knight A, Kazim F, Salvatori V A
Ann Allergy. 1986 Nov;57(5):348-54.
Twenty-six patients with perennial rhinorrhea were treated by Atrovent, the anticholinergic agent, or placebo in a randomized double-blind crossover trial. The severity and duration of rhinorrhea were significantly reduced by Atrovent. Local side effects were more frequent with the active drug. These were reduced in a later open trial by a reduction in dosage.
在一项随机双盲交叉试验中，26名常年性鼻漏患者接受了抗胆碱能药物异丙托溴铵（Atrovent）或安慰剂治疗。Atrovent可显著减轻鼻漏的严重程度和持续时间。使用活性药物时局部副作用更为常见。在随后的开放试验中，通过减少剂量降低了这些副作用。
