Park Min Y, Fletcher John P, Hoffmann Carmen, Lance Alice, Gavegan Fiona, Hitos Kerry
The University of Sydney, Westmead Clinical School, Westmead Hospital, Westmead, Sydney, Australia.
Westmead Research Centre for Evaluation of Surgical Outcomes, Westmead, Sydney, Australia.
Int Angiol. 2018 Oct;37(5):411-418. doi: 10.23736/S0392-9590.18.03969-X. Epub 2018 Feb 19.
Hospitalized patients are at high risk of venous thromboembolism (VTE). Underutilization of thromboprophylaxis remains common despite existing clinical guidelines. The aim is to evaluate the implementation of a state wide standardized adult VTE risk assessment tool (RAT) to assist in the screening of inpatients and prescribing of appropriate thromboprophylaxis.
In total, 234 patients were audited using clinical notes and spot assessments for VTE risk at Western Sydney Local Health District over a two year period. Patients were stratified into pre- (N.=132) and postimplementation (N.=102) of the RAT. Intervention involved continuing education of staff and passive dissemination of guidelines. Prescription of pharmacological and mechanical prophylaxis and the development of thromboembolic events were evaluated.
Overall, 39.0% of medical and 63.0% of surgical patients were risk assessed during preimplementation versus 39.2% and 92.2% during postimplementation of the RAT (P<0.0001). Usage of pharmacological prophylaxis increased from 72% to 79% and mechanical prophylaxis from 41% to 48%. VTE rates in moderate to high risk medical patients decreased from 15.2% preimplementation to 6.5% postimplementation. Rates of non-fatal and fatal pulmonary embolism (PE) were 2.3% and 0.8% respectively prior compared to 1.0% and 0.0% postimplementation.
Standardized VTE RAT increased thromboprophylaxis usage and decreased PE rates, with a greater improvement reflected in surgical patients. These findings highlight the importance of a multifaceted approach to VTE prevention using regular audits with feedback, electronic reminders systems, prescribing tools and continuing education.
住院患者发生静脉血栓栓塞症(VTE)的风险很高。尽管有现有的临床指南,但血栓预防措施的使用不足仍然很常见。目的是评估全州范围内标准化的成人VTE风险评估工具(RAT)的实施情况,以协助筛查住院患者并开具适当的血栓预防药物。
在两年时间里,对西悉尼地方卫生区的234名患者使用临床记录和VTE风险现场评估进行审核。患者被分为RAT实施前(N = 132)和实施后(N = 102)两组。干预措施包括对工作人员的继续教育和指南的被动传播。评估了药物和机械预防措施的处方以及血栓栓塞事件的发生情况。
总体而言,在RAT实施前,39.0%的内科患者和63.0%的外科患者进行了风险评估,而在实施后分别为39.2%和92.2%(P<0.0001)。药物预防的使用率从72%提高到79%,机械预防从41%提高到48%。中度至高度风险内科患者的VTE发生率从实施前的15.2%降至实施后的6.5%。实施前非致命性和致命性肺栓塞(PE)的发生率分别为2.3%和0.8%,实施后分别为1.0%和0.0%。
标准化的VTE RAT增加了血栓预防措施的使用并降低了PE发生率,外科患者的改善更为明显。这些发现凸显了采用多方面方法预防VTE的重要性,包括定期审核并反馈、电子提醒系统、处方工具和继续教育。