Rhew Isaac C, Oesterle Sabrina, Coffman Donna, Hawkins J David
1 Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
2 Social Development Research Group, University of Washington, Seattle, WA, USA.
Eval Health Prof. 2018 Jun;41(2):270-289. doi: 10.1177/0163278718759397. Epub 2018 Feb 20.
Earlier intention-to-treat (ITT) findings from a community-randomized trial demonstrated effects of the Communities That Care (CTC) prevention system on reducing problem behaviors among youth. In ITT analyses, youth were analyzed according to their original study community's randomized condition even if they moved away from the community over the course of follow-up and received little to no exposure to intervention activities. Using inverse probability weights (IPWs), this study estimated effects of CTC in the same randomized trial among youth who remained in their original study communities throughout follow-up. Data were from the Community Youth Development Study, a community-randomized trial of 24 small towns in the United States. A cohort of 4,407 youth was followed from fifth grade (prior to CTC implementation) to eighth grade. IPWs for one's own moving status were calculated using fifth- and sixth-grade covariates. Results from inverse probability weighted multilevel models indicated larger effects for youth who remained in their study community for the first 2 years of CTC intervention implementation compared to ITT estimates. These effects included reduced likelihood of alcohol use, binge drinking, smokeless tobacco use, and delinquent behavior. These findings strengthen support for CTC as an efficacious system for preventing youth problem behaviors.
一项社区随机试验早期的意向性分析(ITT)结果表明,关爱社区(CTC)预防系统对减少青少年问题行为有效果。在意向性分析中,青少年是根据其最初所在研究社区的随机分组情况进行分析的,即便他们在随访过程中搬离了该社区,且很少或几乎没有接触到干预活动。本研究使用逆概率权重(IPW),在同一随机试验中估计了在整个随访期间一直留在其最初研究社区的青少年中,CTC的效果。数据来自社区青少年发展研究,这是一项在美国24个小镇进行的社区随机试验。对一组4407名青少年从五年级(在实施CTC之前)跟踪到八年级。使用五年级和六年级的协变量计算个人迁移状态的逆概率权重。逆概率加权多级模型的结果表明,与意向性分析估计值相比,在实施CTC干预的前两年留在研究社区的青少年效果更大。这些效果包括饮酒、暴饮、使用无烟烟草和犯罪行为的可能性降低。这些发现强化了对CTC作为预防青少年问题行为有效系统的支持。