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阿姆斯特丹性别焦虑症队列研究(1972-2015):患病率、治疗方法和后悔率的趋势。

The Amsterdam Cohort of Gender Dysphoria Study (1972-2015): Trends in Prevalence, Treatment, and Regrets.

机构信息

Department of Endocrinology, VU University Medical Center, Amsterdam, the Netherlands; Center of Expertise on Gender Dysphoria, VU University Medical Center, Amsterdam, the Netherlands.

Center of Expertise on Gender Dysphoria, VU University Medical Center, Amsterdam, the Netherlands; Department of Child and Adolescent Psychiatry, VU University Medical Center, Amsterdam, the Netherlands.

出版信息

J Sex Med. 2018 Apr;15(4):582-590. doi: 10.1016/j.jsxm.2018.01.016. Epub 2018 Feb 17.

DOI:10.1016/j.jsxm.2018.01.016
PMID:29463477
Abstract

BACKGROUND

Over the past decade, the number of people referred to gender identity clinics has rapidly increased. This raises several questions, especially concerning the frequency of performing gender-affirming treatments with irreversible effects and regret from such interventions.

AIM

To study the current prevalence of gender dysphoria, how frequently gender-affirming treatments are performed, and the number of people experiencing regret of this treatment.

METHODS

The medical files of all people who attended our gender identity clinic from 1972 to 2015 were reviewed retrospectively.

OUTCOMES

The number of (and change in) people who applied for transgender health care, the percentage of people starting with gender-affirming hormonal treatment (HT), the estimated prevalence of transgender people receiving gender-affirming treatment, the percentage of people who underwent gonadectomy, and the percentage of people who regretted gonadectomy, specified separately for each year.

RESULTS

6,793 people (4,432 birth-assigned male, 2,361 birth-assigned female) visited our gender identity clinic from 1972 through 2015. The number of people assessed per year increased 20-fold from 34 in 1980 to 686 in 2015. The estimated prevalence in the Netherlands in 2015 was 1:3,800 for men (transwomen) and 1:5,200 for women (transmen). The percentage of people who started HT within 5 years after the 1st visit decreased over time, with almost 90% in 1980 to 65% in 2010. The percentage of people who underwent gonadectomy within 5 years after starting HT remained stable over time (74.7% of transwomen and 83.8% of transmen). Only 0.6% of transwomen and 0.3% of transmen who underwent gonadectomy were identified as experiencing regret.

CLINICAL IMPLICATIONS

Because the transgender population is growing, a larger availability of transgender health care is needed. Other health care providers should familiarize themselves with transgender health care, because HT can influence diseases and interact with medication. Because not all people apply for the classic treatment approach, special attention should be given to those who choose less common forms of treatment.

STRENGTHS AND LIMITATIONS

This study was performed in the largest Dutch gender identity clinic, which treats more than 95% of the transgender population in the Netherlands. Because of the retrospective design, some data could be missing.

CONCLUSION

The number of people with gender identity issues seeking professional help increased dramatically in recent decades. The percentage of people who regretted gonadectomy remained small and did not show a tendency to increase. Wiepjes CM, Nota NM, de Blok CJM, et al. The Amsterdam Cohort of Gender Dysphoria Study (1972-2015): Trends in Prevalence, Treatment, and Regrets. J Sex Med 2018;15:582-590.

摘要

背景

在过去的十年中,寻求性别认同诊所治疗的人数迅速增加。这引发了几个问题,尤其是关于进行具有不可逆影响的性别肯定治疗的频率以及此类干预措施的后悔率。

目的

研究当前性别焦虑症的流行程度,进行性别肯定治疗的频率,以及对这种治疗感到后悔的人数。

方法

回顾性审查了 1972 年至 2015 年间所有在我们性别认同诊所就诊的人的医疗档案。

结果

从 1972 年到 2015 年,有 6793 人(4432 名男性出生分配,2361 名女性出生分配)在我们的性别认同诊所就诊。每年评估的人数增加了 20 倍,从 1980 年的 34 人增加到 2015 年的 686 人。2015 年荷兰的估计患病率为每 3800 名男性(跨性别女性)和每 5200 名女性(跨性别男性)中有 1 人。在首次就诊后 5 年内开始 HT 的人数百分比随时间推移而下降,1980 年为 90%,2010 年为 65%。在开始 HT 后 5 年内接受性腺切除术的人数百分比随时间推移保持稳定(跨性别女性为 74.7%,跨性别男性为 83.8%)。只有 0.6%的接受性腺切除术的跨性别女性和 0.3%的跨性别男性表示后悔。

临床意义

由于跨性别者群体不断增加,因此需要提供更多的跨性别者健康护理。其他医疗保健提供者应熟悉跨性别者健康护理,因为 HT 会影响疾病并与药物相互作用。由于并非所有人都申请经典的治疗方法,因此应特别注意那些选择不太常见的治疗方法的人。

局限性

本研究是在荷兰最大的荷兰性别认同诊所进行的,该诊所治疗了荷兰 95%以上的跨性别者。由于回顾性设计,可能会丢失一些数据。

结论

在最近几十年中,寻求专业帮助的性别认同问题人数急剧增加。对性腺切除术感到后悔的人数仍然很少,并且没有显示出增加的趋势。

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