Department of Clinical Medicine and Therapeutics, School of Medicine, College of Health sciences, University of Nairobi, P O Box 30197-0100, Nairobi, Kenya.
Department of Clinical Medicine and Therapeutics, School of Medicine, College of Health Sciences, University of Nairobi, P O Box 19676-00202, Nairobi, Kenya.
Curr Rheumatol Rep. 2018 Feb 21;20(2):4. doi: 10.1007/s11926-018-0711-y.
Systemic vasculitides are characterized by inflammation of blood vessel walls leading to a myriad of organ disorders depending on the size, site, and location of the affected blood vessel. The epidemiology of vasculitis in the developing world has been inadequately documented. The description of the vasculitides in Africa, both from hospital series as well as taking into consideration, previous epidemiological studies in the community, indicates that these conditions have been rare until relatively recently. In view of these past observations, this review of publications on the topic looks to shed light on the current state of vasculitis in Africa.
Takayasu and Kawasaki appear to be the most commonly reported vasculitides in Africa. Most of the published reports are from North and South Africa. Furthermore, the contribution of vasculitis associated with infections, and in particular HIV, is significant. There are increasing numbers of publications reflecting a growing recognition of the vasculitides in Africa.
系统性血管炎的特征是血管壁炎症，根据受影响血管的大小、部位和位置，导致多种器官疾病。发展中国家血管炎的流行病学资料记录不足。对非洲血管炎的描述，无论是来自医院系列还是考虑到之前在社区进行的流行病学研究，都表明直到最近这些疾病才较为罕见。鉴于这些过去的观察结果，本主题的出版物综述旨在阐明非洲血管炎的现状。
Takayasu 和 Kawasaki 似乎是非洲报道最多的血管炎。大多数已发表的报告来自北非和南非。此外，与感染相关的血管炎，特别是与 HIV 相关的血管炎，其贡献显著。越来越多的出版物反映出非洲对血管炎的认识不断提高。
