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中国传染病临床实践指南的质量评估。

Quality assessment of clinical practice guidelines for infectious diseases in China.

机构信息

Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, Sichuan, PR China.

出版信息

J Evid Based Med. 2018 May;11(2):95-100. doi: 10.1111/jebm.12293. Epub 2018 Feb 21.

DOI:10.1111/jebm.12293
PMID:29464853
Abstract

AIM

We aimed to appraise the quality of Chinese Society of Infectious Diseases of China Medical Association clinical practice guidelines (CPGs) for infectious diseases in China.

METHODS

We performed the electronic search and hand search on the above-mentioned CPGs for infectious diseases published from January 1997 to October 2017. Each publication was evaluated using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument.

RESULTS

Thirteen guidelines were identified and enrolled for the further evaluation. The median scores of the AGREE II domains across all 13 guidelines were as follows: scope and purpose 73.61% (36.11% to 84.72%), stakeholder involvement 12.50% (8.33% to 20.83%), rigor of development 19.27% (12.50% to 26.04%), clarity of presentation 86.11% (23.61% to 94.44%), applicability 33.33% (26.04% to 50.00%), and editorial independence 8.33% (4.17% to 16.67%). The clarity of presentation domain got the highest score among the six domains. Moreover, when compared the CPGs by the year of publication (2002 to 2006 vs. 2007 to 2017), the quality scores were higher in the CPGs published in the last 10 years than those published before, but with no significant difference.

CONCLUSIONS

The quality score of CPGs for infectious diseases in China from January 1997 to October 2017 was moderate, but had significant shortcomings, especially in the stakeholder involvement and editorial independence domains. However, the AGREE II instrument is useful and feasible for appraising the CPGs and should be applied to develop, implement, and promote the CPGs in China.

摘要

目的

评估中国医师协会感染病分会制定的中国感染病临床实践指南的质量。

方法

我们对 1997 年 1 月至 2017 年 10 月发表的感染病临床实践指南进行了电子和手工检索。使用 AGREE II 工具对每个出版物进行评估。

结果

确定并纳入了 13 项指南进行进一步评估。13 项指南的 AGREE II 各领域中位数评分如下:范围和目的 73.61%(36.11%至 84.72%),利益相关者参与 12.50%(8.33%至 20.83%),制定的严谨性 19.27%(12.50%至 26.04%),表述清晰度 86.11%(23.61%至 94.44%),适用性 33.33%(26.04%至 50.00%),编辑独立性 8.33%(4.17%至 16.67%)。在六个领域中,表述清晰度领域得分最高。此外,按发表年份(2002 年至 2006 年与 2007 年至 2017 年)比较指南时,发现最近 10 年发表的指南质量评分高于之前发表的指南,但差异无统计学意义。

结论

1997 年 1 月至 2017 年 10 月中国感染病临床实践指南的质量评分中等,但存在明显缺陷,特别是在利益相关者参与和编辑独立性方面。然而,AGREE II 工具用于评估指南是有用且可行的,应在中国推广应用于指南的制定、实施和推广。

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