Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Department of Cardiology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
ESC Heart Fail. 2018 Jun;5(3):368-371. doi: 10.1002/ehf2.12274. Epub 2018 Feb 21.
Extracorporeal membrane oxygenation is used for acute respiratory distress syndrome, refractory cardiogenic shock, and out-of-hospital cardiac arrest with uncertain neurological status, and, until recently, it was the only minimally invasive option to achieve biventricular support. However, extracorporeal membrane oxygenation increases left ventricular afterload and requires systemic anticoagulation, which is a major contraindication in the context of thrombolytic therapy following an ischaemic stroke. Conversely, the Impella heart pumps by design unload the ventricle and require minimal anticoagulation. We report the first case of mechanical circulatory supported with Impella CP on the left and Impella RP on the right (Abiomed Inc., Danvers, MA) for acute biventricular failure due to suspected acute myocarditis in the context of thrombolytic therapy for ischaemic stroke.
体外膜肺氧合用于急性呼吸窘迫综合征、难治性心源性休克和院外心脏骤停伴不确定的神经状态,直到最近,它还是实现双心室支持的唯一微创选择。然而,体外膜肺氧合会增加左心室后负荷,并需要全身抗凝,这在溶栓治疗缺血性脑卒中后是一个主要的禁忌证。相反,Impella 心脏泵通过设计减轻心室负荷,需要最小的抗凝。我们报告了首例因溶栓治疗缺血性脑卒中而怀疑急性心肌炎导致急性双心室衰竭的患者,使用左心室的 Impella CP 和右心室的 Impella RP(Abiomed Inc.,Danvers,MA)进行机械循环支持的病例。