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[脉搏波传导时间——无创心输出量测量的又一次尝试。]

[PULSE WAVE TRANSIT TIME - ONE MORE ATTEMPT OF NON-INVASIVE CARDIAC OUTPUT MEASUREMENT.].

作者信息

Akselrod B A, Tolstova L A, Pshenichniy T A, Fedulova S V

出版信息

Anesteziol Reanimatol. 2017 Sep;61:178-182.

PMID:29465201
Abstract

BACKGROUND

Estimated continuous cardiac output (esCCOTM) based on pulse wave transit time is one of alternative non-invasive CO measurement techniques.

METHODS

Randomized study included 23 scheduled patients operated upon due to cardiovascular diseases. Cardiac index (CI) was measured Comparative analyses of esCCO and others CO measurement methods used intraoperative was carried out. In the first group (n = 9) esCCO was compared with transpulmonary thermodilution (PiCCO-plus); in the second group (n = 8) - with pulmonary artery thermodilution; in the third group (n = 6) - with transoesophageal echocardiography (velocity-time integral).

RESULTS

In the 1st group direct correlation was found (r = 0,773, p <0.0001), but overestimation was found in 39% of cases; underestimation in 4%. The 2nd group showed direct correlation (r = 0.586, p <0.0001). The 3d group showed direct relationship (r = 0.68, p = 0.0018), but 66.7% of the measurements were out of reference interval (more than ? 15%). Blend- Altman method showed the dispersion of results in all groups.

CONCLUSIONS

  1. Estimated continuous cardiac output measurement technique based on PWTT has a direct correla- tion with prepulmonary thermodilution and transoesophageal echocardiography, medium and high power respectively. 2. esCCO has significant differences with the referential techniques during general anesthesia in cardiac surgery pa- tients. 3. Calibration based on invasive blood pressure and outside cardiac output measurement does not increase the accuracy of measurements. 4. esCCO has a negative diagnostic value and cannot be recommendedfor the cardiac out- put evaluation during cardiac surgery. 5. This method can be useful for analyze general effectiveness of perioperative hemodynamics.
摘要

背景

基于脉搏波传播时间的连续心输出量估算(esCCOTM)是一种替代性的非侵入性心输出量测量技术。

方法

随机研究纳入了23例因心血管疾病而接受手术的患者。测量心脏指数(CI),并对术中使用的esCCO与其他心输出量测量方法进行比较分析。第一组(n = 9)将esCCO与经肺热稀释法(PiCCO-plus)进行比较;第二组(n = 8)与肺动脉热稀释法进行比较;第三组(n = 6)与经食管超声心动图(速度-时间积分)进行比较。

结果

第一组发现直接相关性(r = 0.773,p <0.0001),但39%的病例存在高估;4%的病例存在低估。第二组显示直接相关性(r = 0.586,p <0.0001)。第三组显示直接关系(r = 0.68,p = 0.0018),但66.7%的测量值超出参考区间(超过±15%)。Bland-Altman方法显示所有组结果均有离散度。

结论

1.基于脉搏波传播时间的连续心输出量测量技术与肺前热稀释法和经食管超声心动图分别具有中等和高度的直接相关性。2.在心脏手术患者全身麻醉期间,esCCO与参考技术存在显著差异。3.基于有创血压和心输出量测量之外的校准并不能提高测量准确性。4.esCCO具有负诊断价值,不推荐用于心脏手术期间的心输出量评估。5.该方法可用于分析围手术期血流动力学的总体有效性。

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