Li-Ping Qi, Hong-Wei Liu, Chang-Ming Hong, Yong-Yi Bai, Ang Li
Department of Cardiology, National Center for Clinical Medicine of Geriatric Diseases, The Second Clinical Center, Chinese PLA General Hospital, Beijing, China.
Front Cardiovasc Med. 2022 Oct 19;9:910898. doi: 10.3389/fcvm.2022.910898. eCollection 2022.
The optimal treatment for elderly patients with severe heart failure depends on the accurate assessment of their hemodynamic status. Due to its less invasive nature, the safety and efficacy of invasive pulse-induced contour cardiac output (PiCCO)-based hemodynamic monitoring remains uncertain.
This was a prospective observational study. Between January 2016 and July 2020, 190 elderly patients with severe heart failure were consecutively enrolled. The PiCCO group (89 patients) and non-invasive hemodynamic monitoring group (101 patients) were observed. Hospital stays results were evaluated.
No significant difference in clinical data ( > 0.05) or the incidence of 1-month mortality (16.0 vs. 35.0%, = 0.141) were observed between groups. The coronary care unit (CCU) stay was shorter in the PiCCO group than in the non-invasive group (40.0 vs. 43.0%, = 0.049). Indicators such as low Extravascular Lung Water Index (EVLWI), high Body Mass Index (BMI), low Pulmonary Artery Pressure (PAP), and high Left Ventricular Ejection Time (LVET), were associated with favorable clinical results.
Early invasive PiCCO monitoring is safe in critically ill elderly patients with severe heart failure. The hospital stay was reduced using PiCCO monitoring. These encouraging PiCCO results favor its use in elderly patients with severe heart failure at CCUs.
老年重症心力衰竭患者的最佳治疗取决于对其血流动力学状态的准确评估。由于基于脉搏指示连续心输出量(PiCCO)的有创血流动力学监测侵入性较小,其安全性和有效性仍不确定。
这是一项前瞻性观察性研究。2016年1月至2020年7月,连续纳入190例老年重症心力衰竭患者。观察PiCCO组(89例患者)和无创血流动力学监测组(101例患者)。评估住院结果。
两组间临床数据(>0.05)或1个月死亡率发生率(16.0%对35.0%,P = 0.141)无显著差异。PiCCO组的冠心病监护病房(CCU)住院时间比无创组短(40.0天对43.0天,P = 0.049)。血管外肺水指数(EVLWI)低、体重指数(BMI)高、肺动脉压(PAP)低和左心室射血时间(LVET)高等指标与良好的临床结果相关。
对于老年重症心力衰竭危重症患者,早期有创PiCCO监测是安全的。使用PiCCO监测可缩短住院时间。这些令人鼓舞的PiCCO结果支持其在CCU老年重症心力衰竭患者中的应用。