Callahan Megan L, Storzbach Daniel
a VA Portland Health Care System , Portland , Oregon , USA.
b Department of Psychiatry , Oregon Health & Science University , Portland , Oregon , USA.
Appl Neuropsychol Adult. 2019 Jul-Aug;26(4):365-373. doi: 10.1080/23279095.2018.1433179. Epub 2018 Feb 21.
The purpose of this study was to examine the unique contribution of posttraumatic stress disorder (PTSD) symptoms on sensory sensitivity following mild traumatic brain injury (mTBI) in an Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF) Veteran sample. We hypothesized that the effect of PTSD on noise and light sensitivity following mTBI would be largely driven by PTSD-related hyperarousal symptoms. We compared the relationships between PTSD, noise sensitivity, and light sensitivity of 49 OEF/OIF Veterans with mTBI to that of 23 OEF/OIF Veterans without mTBI. Results suggest that intrusive experiences were significantly related to noise sensitivity in the mTBI group, while light sensitivity was significantly associated with avoidance. Hyperarousal symptoms significantly accounted for noise sensitivity in the no-blast, non-TBI group, whereas PTSD did not affect light sensitivity in this group. These data suggest that PTSD symptoms may uniquely influence the experience of noise and light sensitivity. As such, treatment targeting specific PTSD symptoms may yield clinically significant improvement in sensory sensitivity.
本研究的目的是在持久自由行动和伊拉克自由行动（OEF/OIF）退伍军人样本中，检验创伤后应激障碍（PTSD）症状对轻度创伤性脑损伤（mTBI）后感觉敏感性的独特影响。我们假设，PTSD对mTBI后噪声和光敏感性的影响在很大程度上是由与PTSD相关的过度觉醒症状驱动的。我们比较了49名患有mTBI的OEF/OIF退伍军人与23名未患mTBI的OEF/OIF退伍军人的PTSD、噪声敏感性和光敏感性之间的关系。结果表明，在mTBI组中，侵入性体验与噪声敏感性显著相关，而光敏感性与回避显著相关。在无爆炸、非TBI组中，过度觉醒症状显著解释了噪声敏感性，而PTSD在该组中不影响光敏感性。这些数据表明，PTSD症状可能独特地影响噪声和光敏感性体验。因此，针对特定PTSD症状的治疗可能会在感觉敏感性方面产生临床上显著的改善。
