University Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Institute of Immunity and Transplantation, Royal Free Hospital and University College London, London, UK.
Rev Med Virol. 2018 Mar;28(2). doi: 10.1002/rmv.1971. Epub 2018 Feb 21.
Dengue fever is the commonest viral haemorrhagic fever worldwide and is a leading cause of morbidity and mortality in the tropics. Dengue viral infections are frequently associated with varying degrees of liver injury. Liver injury is more severe in dengue haemorrhagic fever or severe dengue. We review the current knowledge on liver involvement following dengue viral infections and explore the links between clinical manifestations, pathogenesis, and their impact on management.
登革热是全球最常见的病毒性出血热，也是热带地区发病率和死亡率的主要原因。登革热病毒感染常伴有不同程度的肝损伤。登革出血热或重症登革热患者的肝损伤更为严重。我们回顾了登革热病毒感染后肝脏受累的最新知识，并探讨了临床表现、发病机制及其对治疗的影响之间的联系。
