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拉各斯大学教学医院成年慢性鼻-鼻窦炎患者中鼻道抽吸物的细菌学研究,拉各斯

Bacteriology of middle meatal aspirate of adult patients with chronic rhinosinusitis in Lagos. University Teaching Hospital, Lagos.

作者信息

Oladeji S M, Nwawolo C C, Fasunla A J, Elikwu C J, Ezeamagu C O

出版信息

Afr J Med Med Sci. 2016 Jun;45(2):135-141.

Abstract

BACKGROUND

Chronic rhinosinusitis (CRS) significantly lowers the quality of life of patients. The common use of broad spectrum antibiotics for its treatment may alter the pathogens that promote the persistence of this condition. However, the data concerning the distribution of bacteria species. in patients with CRS are not consistent.

OBJECTIVE

To isolate the common aerobic and anaerobic bacteria from the middle meatal aspirates of adult patients with CRS and determine their antibiotic sensitivity patterns Methods: This was a case-control study of adults with diagnosis of CRS. Middle meatal aspirate and swab were obtained from cases and control respectively for bacteriological studies. Data analysis was done using Statistical package for social sciences (SPSS) version 17 Result: Forty one aerobic bacteria were cultured. Sixty one percent of the aerobic bacteria isolated were gram positive (staphlylococcus.aureus was the most frequently found) organisms while the remaining 39% was gram negative. Fifteen peicent of the cultured isolates yielded mixed growth of both aerobes (Gram positive and gram negative).3(6%) isolates of Bacteroides species were cultured Conclusion: The present study found that Staphylococcus aureus, streptococcus pneumoniae, Proteus mirabilis, Klebsiella spp, Escherichia coli and Bacteroides spp) were the common bacterial flora in the paranasal sinuses of patients with CRS.

摘要

背景

慢性鼻-鼻窦炎(CRS)显著降低患者的生活质量。治疗中广泛使用广谱抗生素可能会改变促使该病持续存在的病原体。然而,关于CRS患者细菌种类分布的数据并不一致。

目的

从成年CRS患者的中鼻道抽吸物中分离常见需氧菌和厌氧菌,并确定其抗生素敏感性模式。方法:这是一项针对确诊为CRS的成年人的病例对照研究。分别从病例组和对照组获取中鼻道抽吸物和拭子进行细菌学研究。使用社会科学统计软件包(SPSS)17版进行数据分析。结果:培养出41株需氧菌。分离出的需氧菌中61%为革兰氏阳性菌(最常见的是金黄色葡萄球菌),其余39%为革兰氏阴性菌。15%的培养分离物产生需氧菌(革兰氏阳性菌和革兰氏阴性菌)混合生长。培养出3株(6%)拟杆菌属菌株。结论:本研究发现金黄色葡萄球菌、肺炎链球菌、奇异变形杆菌、克雷伯菌属、大肠杆菌和拟杆菌属是CRS患者鼻窦中的常见菌群。

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