Hu S P, Felice L J, Sivanandan V, Maheswaran S K
Infect Immun. 1986 Dec;54(3):804-10. doi: 10.1128/iai.54.3.804-810.1986.
Pasteurella multocida grown under conditions of iron deprivation secreted into the culture medium a growth-enhancing factor which functioned as a siderophore. The siderophore was found to be neither a phenolate nor a hydroxamate by chemical tests and bioassays and was given the trivial name multocidin. Multocidin was partially purified and found to be a highly polar, nonaromatic, and dialyzable compound. This is the first report demonstrating the production of a siderophore by P. multocida.
在缺铁条件下生长的多杀巴斯德菌会向培养基中分泌一种具有生长促进作用的因子,该因子作为一种铁载体发挥作用。通过化学测试和生物测定发现,这种铁载体既不是酚盐也不是异羟肟酸,并被赋予了俗名多杀菌素。多杀菌素经过部分纯化,发现是一种高度极性、非芳香且可透析的化合物。这是关于多杀巴斯德菌产生铁载体的首次报道。