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[小肾肿块(<4厘米)的标准手术]

[Standard surgery for small renal masses (<4 cm)].

作者信息

Frees S K, Mager R, Borgmann H, Jäger W, Thomas C, Haferkamp A

机构信息

Klinik und Poliklinik für Urologie und Kinderurologie, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.

出版信息

Urologe A. 2018 Mar;57(3):280-284. doi: 10.1007/s00120-018-0583-9.

DOI:10.1007/s00120-018-0583-9
PMID:29468282
Abstract

BACKGROUND

Several new treatment strategies have emerged in the treatment of small renal masses (<4 cm in diameter). Active surveillance and ablative techniques have been introduced but it remains unclear which patients will benefit the most from these new treatment options. A surgical approach remains standard of care. In recent decades, radical nephrectomy has been replaced by nephron-sparing surgery for the management of small renal masses.

RESULTS

In addition to the open partial nephrectomy, which is considered the standard approach, the number of surgeries performed using minimally invasive techniques is increasing. Recent data show that there might be some benefits such as less blood loss. The disadvantages shown by laparoscopic partial nephrectomy such as prolonged warm ischemia, longer operation times, and postoperative renal impairment might be negligible for the robotic approach. Therefore, current guidelines allow these approaches in addition to open partial nephrectomy if sufficient surgical expertise is given.

摘要

背景

在小肾肿块(直径<4厘米)的治疗中出现了几种新的治疗策略。主动监测和消融技术已被引入,但仍不清楚哪些患者将从这些新的治疗选择中获益最大。手术方法仍然是标准的治疗方式。近几十年来,根治性肾切除术已被保留肾单位手术所取代,用于治疗小肾肿块。

结果

除了被认为是标准方法的开放性部分肾切除术外,使用微创技术进行的手术数量正在增加。最近的数据表明,可能存在一些益处,如失血较少。腹腔镜部分肾切除术所显示的缺点,如长时间的热缺血、更长的手术时间和术后肾功能损害,对于机器人手术方法来说可能微不足道。因此,如果有足够的手术专业知识,目前的指南除了开放性部分肾切除术外,也允许采用这些方法。

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本文引用的文献

1
Nephron-sparing Suture of Renal Parenchyma After Partial Nephrectomy: Which Technique to Go For? Some Best Practices.肾部分切除术后肾实质的肾单位保留缝合:选择哪种技术?一些最佳实践。
Eur Urol Focus. 2019 Jul;5(4):600-603. doi: 10.1016/j.euf.2017.08.006. Epub 2017 Aug 30.
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Intravenous Mannitol Versus Placebo During Partial Nephrectomy in Patients with Normal Kidney Function: A Double-blind, Clinically-integrated, Randomized Trial.静脉注射甘露醇与安慰剂在肾功能正常的部分肾切除术中的比较:一项双盲、临床整合、随机试验。
Eur Urol. 2018 Jan;73(1):53-59. doi: 10.1016/j.eururo.2017.07.038. Epub 2017 Aug 16.
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Renal Preservation and Partial Nephrectomy: Patient and Surgical Factors.
肾脏保存与肾部分切除术:患者因素与手术因素
Eur Urol Focus. 2016 Dec 15;2(6):589-600. doi: 10.1016/j.euf.2017.02.012. Epub 2017 Mar 16.
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Treatment of Patients with Positive Margins after Partial Nephrectomy.肾部分切除术后切缘阳性患者的治疗
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Positive Surgical Margins Increase Risk of Recurrence after Partial Nephrectomy for High Risk Renal Tumors.高风险肾肿瘤行部分肾切除术时,阳性切缘增加肿瘤复发风险。
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Comparison of partial nephrectomy and percutaneous ablation for cT1 renal masses.部分肾切除术与经皮消融术治疗 cT1 期肾肿瘤的比较。
Eur Urol. 2015 Feb;67(2):252-9. doi: 10.1016/j.eururo.2014.07.021. Epub 2014 Aug 6.
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Positive surgical margins in nephron-sparing surgery: risk factors and therapeutic consequences.保留肾单位手术中的手术切缘阳性:危险因素及治疗后果
World J Surg Oncol. 2014 Aug 8;12:252. doi: 10.1186/1477-7819-12-252.
9
Prognostic Factors Influencing Postoperative Development of Chronic Kidney Disease in Patients with Small Renal Tumors who Underwent Partial Nephrectomy.影响接受部分肾切除术的小肾肿瘤患者术后慢性肾脏病发生的预后因素
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10
Extent of lymph node dissection at nephrectomy affects cancer-specific survival and metastatic progression in specific sub-categories of patients with renal cell carcinoma (RCC).肾切除术时淋巴结清扫范围影响肾细胞癌(RCC)特定亚组患者的癌症特异性生存率和转移进展。
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