Yoshiya S, Andrish J T, Manley M T, Kurosaka M
J Orthop Res. 1986;4(4):475-85. doi: 10.1002/jor.1100040411.
The purpose of this study was to investigate the biological and biomechanical properties of anterior cruciate ligament (ACL) reconstruction augmented with Dacron prostheses of three different stiffnesses. The ACLs of 36 adult mongrel dogs were removed and the ligament was reconstructed. In 18 dogs, one knee was reconstructed with patellar tendon alone, and the contralateral knee with Dacron augmented patellar tendon. In the remaining 18 dogs, reconstruction was with Dacron augmented patellar tendon with Dacron alone being used for the contralateral control knee. Death was 3 months after surgery, and the reconstructions were examined biologically and biomechanically. The mechanical data were compared with immediate postoperative data obtained from 45 reconstructed fresh cadaveric knees. Tensile testing demonstrated that an increase in failure load was found when the implanted patellar tendon graft was compared with the cadaveric reconstruction. The strength of the Dacron augmented reconstruction showed little change while the Dacron alone graft decreased in strength during the period of implantation. No clear difference was found between the performance of augmentation devices of different stiffnesses. Microangiography showed that grafts were totally revascularized in patellar tendon alone, but not well revascularized in Dacron augmented patellar tendon and Dacron alone reconstruction. The presence of the Dacron appeared to have an adverse effect on revascularization.
本研究的目的是调查用三种不同刚度的涤纶假体增强前交叉韧带（ACL）重建的生物学和生物力学特性。切除36只成年杂种犬的ACL并进行韧带重建。在18只犬中，一侧膝关节仅用髌腱重建，对侧膝关节用涤纶增强髌腱重建。在其余18只犬中，用涤纶增强髌腱重建，对侧对照膝关节仅用涤纶。术后3个月处死动物，对重建物进行生物学和生物力学检查。将力学数据与从45个新鲜尸体膝关节重建后立即获得的数据进行比较。拉伸试验表明，与尸体重建相比，植入的髌腱移植物的破坏载荷增加。在植入期间，涤纶增强重建的强度变化不大，而仅用涤纶的移植物强度下降。不同刚度的增强装置的性能之间未发现明显差异。微血管造影显示，仅髌腱中的移植物完全再血管化，但涤纶增强髌腱和仅涤纶重建中的移植物再血管化不佳。涤纶的存在似乎对再血管化有不利影响。
