Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.
Endocrine. 2018 May;60(2):240-245. doi: 10.1007/s12020-018-1553-0. Epub 2018 Feb 21.
Shear wave elastography (SWE) was described as valuable tool in the diagnostics of distinct types of thyroid lesions, thyroiditis and several other non-thyroidal conditions, such as liver inflammation and fibrosis or diagnostics of breast lesions. The aim of the current study was to assess the appearance of parathyroid adenomas in SWE and to check prospectively if SWE can be valuable additional tool in the diagnostics of pathologically enlarged parathyroids.
Patients with parathyroid adenomas confirmed by histopathology were included. Subjects with benign thyroid lesions were enrolled to the control group. Elasticity of parathyroid adenomas and benign thyroid nodules was measured and compared.
Sixty five patients with parathyroid adenomas and 35 patients with 51 benign thyroid nodules were included. Parathyroid adenomas where significantly more elastic than benign thyroid nodules-mean elasticity of the lesion was 5.2 ± 7.2 vs. 24.3 ± 33.8 kPa, respectively. Relative mean elasticity (in comparison with surrounding thyroid tissue) was 0.30 ± 0.36 and 2.8 ± 3.9, respectively.
SWE can be useful tool in the diagnostics of parathyroid adenomas. Enlarged parathyroids are significantly more elastic than benign thyroid lesions. Low elasticity of the lesion constitutes feature with high negative prognostic value, allowing for reliable exclusion of suspicion of parathyroid adenomas.
剪切波弹性成像（SWE）被描述为诊断不同类型甲状腺病变、甲状腺炎和其他几种非甲状腺疾病（如肝脏炎症和纤维化或乳房病变的诊断）的有价值的工具。本研究的目的是评估甲状旁腺腺瘤在 SWE 中的表现，并前瞻性检查 SWE 是否可以成为诊断病理性增大的甲状旁腺的有价值的附加工具。
纳入经组织病理学证实为甲状旁腺腺瘤的患者。将良性甲状腺病变患者纳入对照组。测量并比较甲状旁腺腺瘤和良性甲状腺结节的弹性。
共纳入 65 例甲状旁腺腺瘤患者和 35 例 51 个良性甲状腺结节患者。甲状旁腺腺瘤的弹性明显大于良性甲状腺结节-病变的平均弹性分别为 5.2±7.2kPa 和 24.3±33.8kPa。相对平均弹性（与周围甲状腺组织相比）分别为 0.30±0.36 和 2.8±3.9。
SWE 可作为诊断甲状旁腺腺瘤的有用工具。增大的甲状旁腺比良性甲状腺病变更有弹性。病变的低弹性构成了具有高阴性预后价值的特征，可可靠排除甲状旁腺腺瘤的怀疑。
