Golu Ioana, Sporea Ioan, Moleriu Lavinia, Tudor Anca, Cornianu Marioara, Vlad Adrian, Timar Romulus, Balas Melania, Amzar Daniela, Vlad Mihaela
Department of Endocrinology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Elastography Center, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Int J Endocrinol. 2017;2017:9092120. doi: 10.1155/2017/9092120. Epub 2017 Aug 6.
2D-shear wave elastography (2D-SWE) is a relatively new elastographic technique. The aim of the present study is to determine the values of the elasticity indexes (EI) measured by 2D-SWE in parathyroid benign lesions (adenomas or hyperplasia) and to establish if this investigation is helpful for the preoperative identification of the parathyroid adenoma.
The study groups were represented by 22 patients with primary or tertiary hyperparathyroidism, diagnosed by specific tests, and 43 healthy controls, in whom the thyroid parenchyma was evaluated, in order to compare the EI of the thyroid tissue with those of the parathyroid lesions.
The mean EI measured by 2D-SWE in the parathyroid lesions was 10.2 ± 4.9 kPa, significantly lower than that of the normal thyroid parenchyma (19.5 ± 7.6 kPa; = 0.007), indicating soft tissue. For a cutoff value of 12.5 kPa, the EI assessed by 2D-SWE had a sensitivity of 93% and a specificity of 86% (AUC = 0.949; < 0.001) for predicting parathyroid lesions.
A value lower than 12.5 kPa for the mean EI measured by 2D-SWE can be used to confirm that the lesion/nodule is a parathyroid adenoma.
二维剪切波弹性成像（2D-SWE）是一种相对较新的弹性成像技术。本研究的目的是确定通过二维剪切波弹性成像测量的弹性指数（EI）在甲状旁腺良性病变（腺瘤或增生）中的值，并确定该检查是否有助于甲状旁腺腺瘤的术前识别。
研究组包括22例经特定检查诊断为原发性或继发性甲状旁腺功能亢进的患者以及43例健康对照者，对他们的甲状腺实质进行评估，以便比较甲状腺组织与甲状旁腺病变的弹性指数。
二维剪切波弹性成像测量的甲状旁腺病变的平均弹性指数为10.2±4.9kPa，显著低于正常甲状腺实质（19.5±7.6kPa；P = 0.007），表明为软组织。对于12.5kPa的临界值，二维剪切波弹性成像评估的弹性指数对甲状旁腺病变的预测敏感性为93%，特异性为86%（AUC = 0.949；P < 0.001）。
二维剪切波弹性成像测量的平均弹性指数低于12.5kPa的值可用于确认病变/结节为甲状旁腺腺瘤。
