Eliakim Alon
1 Tel Aviv University.
Pediatr Exerc Sci. 2018 Feb 1;30(1):47-51. doi: 10.1123/pes.2017-0289. Epub 2018 Feb 22.
The Pediatric Exercise Science "Year That Was" section aims to highlight the most important (to the author's opinion) manuscripts that were published in 2017 in the field of endocrinology and pediatric exercise science. This year's selection includes studies showing that 1) in pubertal swimmers, there is a decrease in insulin-like growth factor-1 (IGF-I) and IGF-binding protein-3 (IGFBP-3) during intense training (a catabolic-type hormonal response) with an anabolic "rebound" characterized by a significant increase of these growth factors during training tapering down. Moreover, it was shown that changes of IGF-I and IGFBP-3 paralleled changes in peak and average force but not with endurance properties, showing decreases during intense training and increases during tapering; 2) a meta-analysis showing that growth hormone administration elicits significant changes in body composition and possible limited effect on anaerobic performance but does not increase either muscle strength or aerobic exercise capacity in healthy, young subjects; and 3) short-term exercise intervention can prevent the development of polycystic ovary syndrome in a dose-dependent manner in letrozole-induced polycystic ovary syndrome rat model with high-intensity exercise being most effective. The implication of these studies to the pediatric population, their importance, and the new research avenues that were opened by these studies is emphasized.
《儿科运动科学》的“过去一年”板块旨在突出(作者认为)2017年发表在内分泌学和儿科运动科学领域最重要的手稿。今年的入选研究包括:1)在青春期游泳运动员中,高强度训练期间胰岛素样生长因子-1(IGF-I)和IGF结合蛋白-3(IGFBP-3)会减少(一种分解代谢型激素反应),而在训练强度降低时会出现合成代谢“反弹”,其特征是这些生长因子显著增加。此外,研究表明IGF-I和IGFBP-3的变化与峰值和平均力量的变化平行,但与耐力特性无关,在高强度训练期间减少,在训练强度降低时增加;2)一项荟萃分析表明,在健康的年轻受试者中,生长激素给药会引起身体成分的显著变化,对无氧运动表现可能有有限影响,但不会增加肌肉力量或有氧运动能力;3)在来曲唑诱导的多囊卵巢综合征大鼠模型中,短期运动干预可以以剂量依赖的方式预防多囊卵巢综合征的发展,其中高强度运动最为有效。文中强调了这些研究对儿科人群的意义、其重要性以及这些研究开辟的新研究途径。