Peng-Lei Xiao, Yi-Biao Zhou, Yan Shi, Yan Yang, Jian-Chuan Gao, Xiu-Xia Song, Qing-Wu Jiang
Department of Epidemiology, School of Public Health, Fudan University; Key Laboratory of Public Health Safety, Ministry of Education; Fudan University Center for Tropical Disease Research, Shanghai 200032, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2016 Jan 29;28(2):128-134. doi: 10.16250/j.32.1374.2015191.
To investigate the prevalence and risk factors of helminthic infections including , and and human immunodeficiency virus (HIV), and find out the association among them in a rural community of southwestern China.
A community-based cross sectional study was conducted. One town was selected randomly; the infections of , and were detected with the modified Kato-Katz thick smear method and HIV infection with the diagnostic Test Kit among all residents. A questionnaire survey was conducted to investigate the related risk factors.
Among the participants, the infection rates of HIV, , and were 2.33%, 2.05%, 13.47% and 30.59% respectively; 7.08% (31/438) were infected with both and ; 0.23% (1/438) were co-infected with HIV and , and the same with HIV and The multivariate logistic regression analysis showed that sex (male, =3.26, 95% ：0.97, 10.95) and drug abuse (=72.86, 95% ：18.51, 286.76) were significantly associated with HIV infection. Home toilet was negatively related to infection (=0.52, 95% ：0.27, 0.98) and infection (=0.48, 95% ：0.28, 0.80). Compared with the people in Villages Four, the people living in Village One were at a higher risk for infection (=3.14, 95% ：1.35, 7.27), and compared with the people living in Village Four, the people living in Village Two and Village Three were more likely to be infected with (=3.73, 95% ：1.92, 7.26; =4.53, 95% ：2.12, 9.68). The people aged between 11 and 20 years had a higher infection risk than the people aged more than 50 years ( = 3.72, 95% ：1.59, 8.67). There was a significant association between and infections ( = 3.11, 95% ：1.63, 5.93). There was no association between infection and related factors above mentioned.
The infection rates of HIV, , and especially were rather high in this area, and therefore, the prevention and treatment of these diseases should be strengthened. Further studies on the relationship between HIV and the infections of helminths, especially are needed.
调查包括[寄生虫名称1]、[寄生虫名称2]和[寄生虫名称3]在内的蠕虫感染及人类免疫缺陷病毒（HIV）的流行情况和危险因素，并了解中国西南部一个农村社区中它们之间的关联。
开展一项基于社区的横断面研究。随机选取一个镇；采用改良加藤厚涂片法检测所有居民的[寄生虫名称1]、[寄生虫名称2]和[寄生虫名称3]感染情况，并用诊断试剂盒检测HIV感染情况。进行问卷调查以调查相关危险因素。
在参与者中，HIV、[寄生虫名称1]、[寄生虫名称2]和[寄生虫名称3]的感染率分别为2.33%、2.05%、13.47%和30.59%；7.08%（31/438）同时感染了[寄生虫名称1]和[寄生虫名称2]；0.23%（1/438）同时感染了HIV和[寄生虫名称1]，HIV和[寄生虫名称2]同时感染的情况相同。多因素逻辑回归分析显示，性别（男性，比值比=3.26，95%可信区间：0.97，10.95）和药物滥用（比值比=72.86，95%可信区间：18.51，286.76）与HIV感染显著相关。家庭厕所与[寄生虫名称1]感染（比值比=0.52，95%可信区间：0.27，0.98）和[寄生虫名称2]感染（比值比=0.48，95%可信区间：0.28，0.80）呈负相关。与四村的人相比，一村的人感染[寄生虫名称1]的风险更高（比值比=3.14，95%可信区间：1.35，7.27），与四村的人相比，二村和三村的人感染[寄生虫名称2]的可能性更大（比值比=3.73，95%可信区间：1.92，7.26；比值比=4.53，95%可信区间：2.12，9.68）。11至20岁的人感染[寄生虫名称2]的风险高于50岁以上的人（比值比=3.72，95%可信区间：1.59，8.67）。[寄生虫名称1]和[寄生虫名称2]感染之间存在显著关联（比值比=3.11，95%可信区间：1.63，5.93）。[寄生虫名称3]感染与上述相关因素之间无关联。
该地区HIV、[寄生虫名称1]、[寄生虫名称2]尤其是[寄生虫名称3]的感染率相当高，因此应加强这些疾病的防治。需要进一步研究HIV与蠕虫感染尤其是[寄生虫名称2]感染之间的关系。
