[Genetic variation of among isolates collected from patients in Zunyi City, Guizhou Province].
作者信息
Ming-Hui Zheng, Chang-Lin Ye, Nan Jiang, Bo Luo, Yu-Juan Shen, Li-Fang He, Hui Liu
机构信息
Department of Parasitology, School of Basic Medicine, Zunyi Medical University, Guizhou Province, Zunyi 563003, China.
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, China.
出版信息
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2017 Sep 27;29(5):598-601. doi: 10.16250/j.32.1374.2017090.
OBJECTIVE
To identify the genetic variation and possible sources of isolates collected from patients in Zunyi City, Guizhou Province.
METHODS
Seven cases of infection in Zunyi City, 2016 were verified, and DNA (s) were extracted from the 's body collected from the thelaziasis patients. A mitochondrial COX1 fragment was amplified and sequenced. The sequence alignment and phylogenetical analysis were performed to compare the genetic variation of the gene sequence with the homologous sequences downloaded from Genebank.
RESULTS
COX1 genes of were differed among the samples from the seven cases, which had low variation.
CONCLUSIONS
Zunyi City is a new area with endemic of thelaziasis. The isolates from Zunyi City include either Asian origin or European origin of . Moreover, at least four haplotypes are identified among the seven isolates.
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