Mladenovic Irena, Krunic Jelena, Stojanovic Nikola, Markovic Dusanka, de Siqueira Silvia Rdt
J Oral Facial Pain Headache. 2018 Spring;32(2):123–129. doi: 10.11607/ofph.1918. Epub 2018 Feb 21.
To explore the unstimulated salivary flow rate and subjective feeling of oral dryness in young adult women with temporomandibular disorders (TMD) and their relation to the presence of chronic pain, depression, somatization, and limited mandibular mobility.
Unstimulated whole saliva flow rate and presence of oral dryness were determined in 45 women with TMD and 30 healthy controls. The Research Diagnostic Criteria for TMD (RDC/TMD) were used for assessment of TMD, chronic pain, depression, somatization, and mandibular mobility. Factors with P < .05 in the bivariate analysis were included in multivariate modeling.
The TMD patients showed significantly diminished unstimulated salivary flow (P = .010) in comparison to controls, but there was no difference in subjective oral dryness. Within the TMD group, patients with mandibular hypomobility and free from somatization exhibited significantly lower salivary output (P = .037; P = .015, respectively). No relationship between salivary flow and depression or TMD pain was observed. Multivariate linear regression identified somatization as the single variable contributing to salivary flow (P = .044) in the TMD patients.
The present study shows a relationship between TMD and lower salivary flow but no evidence of a relationship between TMD and subjective oral dryness in young adult women. Somatization was the single variable to emerge from the evaluation of potential factors contributing to salivary output in TMD patients.
探讨患有颞下颌关节紊乱病（TMD）的年轻成年女性的静息唾液流速和口腔干燥主观感受，以及它们与慢性疼痛、抑郁、躯体化症状和下颌运动受限之间的关系。
测定了45名患有TMD的女性和30名健康对照者的静息全唾液流速及口腔干燥情况。采用颞下颌关节紊乱病研究诊断标准（RDC/TMD）评估TMD、慢性疼痛、抑郁、躯体化症状和下颌运动情况。双变量分析中P<0.05的因素纳入多变量模型。
与对照组相比，TMD患者的静息唾液流速显著降低（P=0.010），但主观口腔干燥情况无差异。在TMD组中，下颌运动受限且无躯体化症状的患者唾液分泌量显著较低（分别为P=0.037；P=0.015）。未观察到唾液流速与抑郁或TMD疼痛之间的关系。多变量线性回归确定躯体化症状是导致TMD患者唾液流速变化的唯一变量（P=0.044）。
本研究表明TMD与较低的唾液流速之间存在关联，但没有证据表明TMD与年轻成年女性的主观口腔干燥之间存在关联。躯体化症状是评估TMD患者唾液分泌潜在影响因素时唯一出现的变量。
