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雄激素/同化类固醇使用的中枢效应。

The Central Effects of Androgenic-anabolic Steroid Use.

机构信息

Department of Endocrinology, Diabetology & Isotope Treatment, Wrocław Medical University, Wrocław, Poland (MM); and Department of Sports Medicine & Dietetics, University School of Physical Education, Wrocław, Poland (MM, AB, PJ).

出版信息

J Addict Med. 2018 May/Jun;12(3):184-192. doi: 10.1097/ADM.0000000000000395.

DOI:10.1097/ADM.0000000000000395
PMID:29470183
Abstract

: Millions of men use androgenic-anabolic steroids (AAS) to stimulate muscle growth and improve physical appearance. Although 1 out of 3 people who uses androgenic-anabolic steroids develops a steroid use disorder, the effects of the drugs on the central nervous system and the psyche are still not well understood. Although most addictive substances improve mood immediately after administration, AAS exert less pronounced euphoric effects. Instead, they are primarily taken for the delayed gratification of increased muscle mass. Withdrawal from AAS may lead to a range of somatic and psychiatric symptoms, and, in many cases, comprehensive treatment supervised by an endocrinologist and a psychiatrist is required.

摘要

: 数以百万计的男性使用雄激素和合成代谢类固醇(AAS)来刺激肌肉生长和改善身体外观。尽管使用雄激素和合成代谢类固醇的人中每 3 人就有 1 人出现类固醇使用障碍,但这些药物对中枢神经系统和心理的影响仍不为人知。虽然大多数成瘾物质在给药后立即改善情绪,但 AAS 的欣快作用不那么明显。相反,它们主要是为了延迟获得增加的肌肉质量的满足感。AAS 的戒断可能导致一系列躯体和精神症状,在许多情况下,需要在内分泌学家和精神科医生的监督下进行全面治疗。

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