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对治疗合成代谢雄激素类固醇引起的性腺功能减退症的内分泌学家的调查。

Survey of endocrinologists managing recovery from anabolic androgenic steroid induced hypogonadism.

机构信息

Department of Endocrinology and Metabolism, Barts Health NHS Trust, West Smithfield, London.

Section of Investigative Medicine, Imperial College London, Commonwealth Building, Hammersmith Hospital, Du Cane Road, London.

出版信息

Reprod Fertil. 2023 Feb 27;4(1). doi: 10.1530/RAF-22-0097. Print 2023 Jan 1.

Abstract

Anabolic steroids (also known as 'steroids') are banned drugs like testosterone, which make muscles bigger in men. These drugs are dangerous because they stop the testes from making natural testosterone and can cause heart attacks. Men stopping steroids have very low testosterone, which makes them feel weak, depressed, suicidal, infertile, and unable to have erections. We surveyed over 100 doctors to find out how they treat men giving up steroids. We report that doctors differ widely in the way they treat these men. Most doctors simply advise men to wait for the natural recovery of testosterone levels to happen. But 20% of doctors give men drugs to boost testosterone and make men feel better. Unfortunately, many patients had not recovered by the time of our survey. In summary, our survey highlights differences and limitations in the treatment of men giving up steroids. The use of steroids is increasing rapidly among young men, so we recommend further work to improve the treatment of men who are motivated to give up steroids.

摘要

合成代谢类固醇(也称为“类固醇”)是被禁止的药物,如睾丸激素,可使男性肌肉增大。这些药物很危险,因为它们会阻止睾丸产生天然睾丸激素,并可能导致心脏病发作。停止使用类固醇的男性睾丸激素水平非常低,这会使他们感到虚弱、沮丧、有自杀倾向、不育和无法勃起。我们调查了 100 多名医生,以了解他们如何治疗停止使用类固醇的男性。我们报告说,医生在治疗这些男性的方式上存在很大差异。大多数医生只是建议男性等待睾丸激素水平自然恢复。但是 20%的医生会给男性使用药物来提高睾丸激素水平,使他们感觉更好。不幸的是,在我们进行调查时,许多患者还没有恢复。总之,我们的调查突出了治疗停止使用类固醇的男性的差异和局限性。在年轻人中,使用类固醇的情况迅速增加,因此我们建议进一步开展工作,改善有意愿停止使用类固醇的男性的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69c4/9986377/b3740be0b4fd/RAF-22-0097fig1.jpg

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