Rio B, Le Tourneau A, Sobahni I, Audouin J, Bouvet A, Diebold J, Zittoun R
Presse Med. 1986 Sep 20;15(30):1414-6.
Cryptosporidiosis may cause diarrhea after a conditioning regimen for allogeneic bone marrow transplantation. The case reported here suggests resurgence of latent cryptosporidiosis in early post-graft period, since other causes of immunosuppression such as graft-versus-host disease or transfusional LAV/HTLV III retroviral infection, were absent. The diagnosis was confirmed by rectal biopsy and ultrastructural analysis. Good response to spiramycin was obtained.
异体骨髓移植预处理方案后,隐孢子虫病可能导致腹泻。本文报道的病例提示在移植后早期潜伏的隐孢子虫病复发,因为不存在移植物抗宿主病或输血性淋巴细胞脉络丛脑膜炎病毒/人类免疫缺陷病毒III型逆转录病毒感染等其他免疫抑制原因。通过直肠活检和超微结构分析确诊。使用螺旋霉素治疗反应良好。