Brion N, Joly V, Champetier de Ribes D, Meier F, Courtois F, Carbon C
Presse Med. 1986 Oct 25;15(37):1851-4.
During one year syphilis serology was systematically studied, using the TPHA and VDRL tests, in each of the 1,279 patients hospitalized in an Internal Medicine department. In all cases diagnosis and treatment were analyzed by means of a decision algorithm. Only 37 patients were found to have one or both serological tests positive. No evolutive syphilis was observed, and none of these positive tests was contributive to the diagnosis of another disease. Only 14 patients received a specific antibiotic treatment on the grounds that their positive test confirmed a late asymptomatic syphilis. We conclude that systematic syphilis serological tests are not useful in an Internal Medicine department, except in some patients epidemiologically at high risk of syphilis.
在一年时间里，我们使用梅毒螺旋体血细胞凝集试验（TPHA）和性病研究实验室玻片试验（VDRL），对内科住院的1279例患者逐一进行了梅毒血清学的系统研究。所有病例均通过决策算法进行诊断和治疗分析。仅发现37例患者一项或两项血清学检测呈阳性。未观察到梅毒进展情况，且这些阳性检测结果均无助于其他疾病的诊断。仅14例患者因阳性检测结果确诊为晚期无症状梅毒而接受了特效抗生素治疗。我们得出结论，在内科进行系统性梅毒血清学检测并无用处，除非某些患者在流行病学上处于梅毒高风险。
