病毒诱导的免疫抑制。

Virus-induced immunosuppression.

作者信息

Horohov D W, Rouse B T

出版信息

Vet Clin North Am Small Anim Pract. 1986 Nov;16(6):1097-127. doi: 10.1016/s0195-5616(86)50131-5.

Abstract

Infection with a variety of viruses results in the suppression of the host's immune system. Several mechanisms thought to be responsible for this effect are discussed: infection and alteration of lymphocytes and macrophages, production of soluble suppressor factors, and the induction of suppressor cells. The clinical significance of virus-induced immunosuppression is also discussed.

摘要

感染多种病毒会导致宿主免疫系统受到抑制。本文讨论了几种被认为是造成这种效应的机制：淋巴细胞和巨噬细胞的感染与改变、可溶性抑制因子的产生以及抑制细胞的诱导。还讨论了病毒诱导的免疫抑制的临床意义。