Xpert Mtb/Rif Ultra 检测在儿童肺结核诊断中的准确性。
Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children.
机构信息
From the Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, National Health Laboratory Service.
Department of Paediatrics and Child Health, MRC Unit on Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
出版信息
Pediatr Infect Dis J. 2018 Oct;37(10):e261-e263. doi: 10.1097/INF.0000000000001960.
We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same specimen. Of those children with microbiologically confirmed tuberculosis (positive Xpert, Ultra or culture), Xpert detected 63.2%, Ultra 73.7% and culture 82.9%.
我们使用银行存储的诱导痰来确定新的 Xpert MTB/RIF Ultra 检测在诊断儿童肺结核方面的准确性。与同一样本的培养结果相比，其敏感性和特异性分别为 75.3%和 96.9%。在那些经微生物学确诊为结核病的儿童中（Xpert、Ultra 或培养均为阳性），Xpert 检测出 63.2%，Ultra 检测出 73.7%，培养检测出 82.9%。
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