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小儿创伤的损伤控制性复苏。

Damage control resuscitation in pediatric trauma.

机构信息

Division of Emergency Medicine, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

出版信息

Curr Opin Pediatr. 2018 Jun;30(3):338-343. doi: 10.1097/MOP.0000000000000617.

Abstract

PURPOSE OF REVIEW

Damage control resuscitation is an overall management strategy used in trauma patients to rapidly restore physiologic stability, while mitigating hypothermia, coagulopathy and acidosis. We review the evidence and current practice of damage control resuscitation in pediatric trauma patients with a specific focus on fluid management.

RECENT FINDINGS

There have been a number of studies over the last several years examining crystalloid fluid resuscitation, balanced blood product transfusion practice and hemostatic agents in pediatric trauma. Excessive fluid resuscitation has been linked to increased number of ICU days, ventilator days and mortality. Balanced massive transfusion (1 : 1 : 1 product ratio) has not yet been demonstrated to have the same mortality benefits in pediatric trauma patients as in adults. Similarly, tranexamic acid (TXA) has strong evidence to support its use in adult trauma and some evidence in pediatric trauma.

SUMMARY

Attention to establishing rapid vascular access and correcting hypothermia and acidosis is essential. A judicious approach to crystalloid resuscitation in the bleeding pediatric trauma patient with early use of blood products in keeping with an organized approach to massive hemorrhage is recommended. The ideal crystalloid volumes and/or blood product ratios in pediatric trauma patients have yet to be determined.

摘要

目的综述

损伤控制性复苏是一种在创伤患者中广泛应用的整体管理策略,用于快速恢复生理稳定性,同时减轻低体温、凝血障碍和酸中毒。我们综述了损伤控制性复苏在儿科创伤患者中的证据和当前实践,特别关注液体管理。

最近的发现

近年来,已有多项研究探讨了晶体液复苏、平衡的血制品输注实践和止血剂在儿科创伤中的应用。过度液体复苏与 ICU 天数、呼吸机天数和死亡率增加有关。平衡的大量输血(1:1:1 制品比例)尚未在儿科创伤患者中表现出与成人相同的死亡率益处。同样,氨甲环酸(TXA)在成人创伤中有强有力的证据支持其使用,在儿科创伤中也有一些证据支持。

总结

快速建立血管通路和纠正低体温和酸中毒至关重要。对于出血性儿科创伤患者,建议采用明智的晶体液复苏方法,并早期使用血制品,以配合大出血的规范化处理。儿科创伤患者的理想晶体液量和/或血制品比例尚未确定。

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