Wenz W, Mohorn M, Jäger L
Allerg Immunol (Leipz). 1986;32(3):215-22.
In 2 clinical studies we tested the efficacy of ketotifen in allergic rhinitis and allergic bronchial asthma. Ketotifen was demonstrated to have a convincing effect not only upon the typical inhalation allergens, such as pollen, house dust mite or animal hair, but also upon allergens ingested via the gastrointestinal tract (food). As even long-term administration has thus far not shown toxic side-effects, ketotifen, based on appropriate indication, can already in childhood be successfully applied.
在两项临床研究中,我们测试了酮替芬在过敏性鼻炎和过敏性支气管哮喘中的疗效。结果表明,酮替芬不仅对典型的吸入性过敏原,如花粉、屋尘螨或动物毛发有显著效果,而且对经胃肠道摄入的过敏原(食物)也有作用。由于迄今为止即使长期给药也未显示出毒副作用,基于适当的适应症,酮替芬在儿童期即可成功应用。