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基于共轭聚合物纳米粒子的荧光生物传感器用于对苯二酚的超灵敏检测。

Conjugated polymer nanoparticles-based fluorescent biosensor for ultrasensitive detection of hydroquinone.

机构信息

State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, PR China.

State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Viral Disease Control and Prevention, Beijing, PR China.

出版信息

Anal Chim Acta. 2018 Jul 5;1012:60-65. doi: 10.1016/j.aca.2018.01.027. Epub 2018 Jan 24.

DOI:10.1016/j.aca.2018.01.027
PMID:29475474
Abstract

This work describes a simple and sensitive fluorescent method for detection of hydroquinone utilizing conjugated polymer nanoparticles (CPNs). The CPNs serve both as a catalyst to accelerate the conversion of hydroquinone to benzoquinone and a fluorescent probe. In the presence of hydroquinone, the fluorescence of CPNs can be effectively quenched by benzoquinone. The detection limit of hydroquinone was down to 5 nM and excellent selectivity toward possible interferences was obtained. This method was successfully applied for hydroquinone detection in lake water and satisfactory results were achieved.

摘要

本工作描述了一种利用共轭聚合物纳米粒子(CPNs)检测对苯二酚的简单灵敏的荧光方法。CPNs 既可用作催化剂加速对苯二酚转化为苯醌,又可用作荧光探针。在对苯二酚存在下,CPNs 的荧光可被苯醌有效猝灭。对苯二酚的检测限低至 5 nM,并获得了对可能干扰物的优异选择性。该方法成功地应用于湖水对苯二酚的检测,获得了令人满意的结果。

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