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综述:Urolift 有哪些新进展?

Mini-Review: What Is New in Urolift?

机构信息

Department of Urology, Ludwig-Maximilians-University of Munich, Munich, Germany.

Department of Urology, Ludwig-Maximilians-University of Munich, Munich, Germany.

出版信息

Eur Urol Focus. 2018 Jan;4(1):36-39. doi: 10.1016/j.euf.2018.01.013. Epub 2018 Feb 21.

DOI:10.1016/j.euf.2018.01.013
PMID:29475817
Abstract

CONTEXT

Lower urinary tract symptoms (LUTS) are one of the most common benign conditions affecting aging men. Among surgical procedures, minimally invasive treatment options have emerged with the main objective to be at least equally effective as current standard techniques, but with a more favourable safety profile.

OBJECTIVE

To present the technical principle for prostatic urethral lift (PUL) and review clinical outcomes.

EVIDENCE ACQUISITION

Medline, PubMed, the Cochrane database, and Embase were screened for randomised controlled trials, clinical trials, and reviews on PUL.

EVIDENCE SYNTHESIS

Data from the L.I.F.T study proved that PUL can provide rapid and durable relief of LUTS without compromising sexual function. The BPH6 trial compared PUL with transurethral resection of the prostate (TURP), and its outcomes indicated that improvement of LUTS was more pronounced after TURP, whereas PUL was superior in terms of quality of recovery, ejaculatory function, and quality of sleep.

CONCLUSIONS

PUL is an attractive option for selected patients who seek rapid and durable relief of LUTS with complete preservation of sexual function and fast recovery after intervention.

PATIENT SUMMARY

Prostatic urethral lift is an efficient and safe minimally invasive procedure that offers rapid and durable relief of lower urinary tract symptoms without compromising sexual function.

摘要

背景

下尿路症状(LUTS)是影响老年男性的最常见良性疾病之一。在外科手术中,出现了微创治疗选择,其主要目标是至少与当前的标准技术同样有效,但具有更有利的安全性。

目的

介绍前列腺尿道抬高术(PUL)的技术原理并综述临床结果。

证据获取

在 Medline、PubMed、Cochrane 数据库和 Embase 上筛选了关于 PUL 的随机对照试验、临床试验和综述。

证据综合

LIFT 研究的数据证明,PUL 可以快速持久地缓解 LUTS,而不会影响性功能。BPH6 试验比较了 PUL 与经尿道前列腺切除术(TURP),其结果表明 TURP 后 LUTS 改善更明显,而 PUL 在恢复质量、射精功能和睡眠质量方面更具优势。

结论

对于寻求快速持久缓解 LUTS、完全保留性功能和干预后快速恢复的选定患者,PUL 是一种有吸引力的选择。

患者总结

前列腺尿道抬高术是一种高效且安全的微创程序,可快速持久地缓解下尿路症状,而不会影响性功能。

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