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采用全聚乙烯胫骨部件的内侧单髁膝关节置换术的十年生存率及患者报告结局

Ten-year survival and patient-reported outcomes of a medial unicompartmental knee arthroplasty incorporating an all-polyethylene tibial component.

作者信息

Scott Chloe E H, Wade Frazer A, MacDonald Deborah, Nutton Richard W

机构信息

Department of Orthopaedics, Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, Edinburgh, EH16 4SA, UK.

出版信息

Arch Orthop Trauma Surg. 2018 May;138(5):719-729. doi: 10.1007/s00402-018-2908-y. Epub 2018 Feb 23.

Abstract

INTRODUCTION

Biomechanical studies have suggested that proximal tibial strain is elevated in UKAs incorporating all-polyethylene tibial components with concern that this leads to premature failure. This study reports minimum 10-year outcomes for a UKA incorporating an all-polyethylene tibial component to determine whether these concerns were realised.

MATERIALS AND METHODS

109 fixed bearing UKAs (97 patients, mean age 68 (range 48-87), 54/97 (56%) female) with all-polyethylene tibial components were followed up for ≥ 10 years with Oxford Knee Scores, Forgotten Joint Scores and Kaplan-Meier analysis. 106/109 implants were 7 mm, 3 were 9.5 mm.

RESULTS

Ten-year survival was 85.5% (78.6-92.4 95% CI) with the end-point failure for any reason. Unexplained pain was the commonest mode of failure (6/17) followed by lateral compartment osteoarthritis (5/17) and tibial subsidence/loosening (4/17). Revision rate was highest at 2-5 years due to revisions for unexplained pain. Ten-year survival was worse in patients < 65 years old (p = 0.035), in those with BMI > 30 (p = 0.017) and in those with postoperative increases in medial tibial sclerosis (p < 0.001 log-rank). Implant malalignment was not significantly associated with failure. Radioisotope bone scans in 16 patients all remained "hot" at mean 6.1 years (range 2.1-11.5). Relative risk of failure in patients < 65 years was 2.9 (1.2-7.0 95% CI) and when BMI > 30 was 2.9 (1.2-6.9 95% CI). In those with intact UKAs at 10 years, mean Oxford Knee Score was 34.8 ± 10.7, Forgotten Joint Score was 37.9 ± 26.7 and 96% were satisfied with their knee.

CONCLUSION

The high rate of early failure between 2 and 5 years in this all-polyethylene tibial component UKA did not persist in the long term. Though medial proximal tibial metabolic changes appear to persist they are not necessarily symptomatic. BMI > 30 and age < 65 years were significant risk factors for revision.

摘要

引言

生物力学研究表明,在采用全聚乙烯胫骨部件的单髁膝关节置换术中,胫骨近端应变会升高,人们担心这会导致过早失败。本研究报告了采用全聚乙烯胫骨部件的单髁膝关节置换术至少10年的结果,以确定这些担忧是否成为现实。

材料与方法

对109例采用全聚乙烯胫骨部件的固定承重单髁膝关节置换术患者(97例患者,平均年龄68岁(范围48 - 87岁),54/97(56%)为女性)进行了≥10年的随访,采用牛津膝关节评分、遗忘关节评分和Kaplan-Meier分析。106/109枚植入物为7毫米,3枚为9.5毫米。

结果

任何原因导致的10年生存率为85.5%(78.6 - 92.4 95%置信区间)。不明原因疼痛是最常见的失败模式(6/17),其次是外侧间室骨关节炎(5/17)和胫骨下沉/松动(4/17)。由于不明原因疼痛的翻修,2 - 5年的翻修率最高。65岁以下患者的10年生存率较差(p = 0.035),BMI > 30的患者(p = 0.017)以及术后胫骨内侧硬化增加的患者(p < 0.001对数秩检验)也是如此。植入物排列不齐与失败无显著相关性。16例患者的放射性核素骨扫描在平均6.1年(范围2.1 - 11.5年)时均仍为“热区”。65岁以下患者失败的相对风险为2.9(1.2 - 7.0 95%置信区间),BMI > 30时为2.9(1.2 - 6.9 95%置信区间)。在10年时膝关节置换术完好的患者中,牛津膝关节平均评分为34.8 ± 10.7,遗忘关节评分为37.9 ±

26.7,96%的患者对其膝关节满意。

结论

这种全聚乙烯胫骨部件单髁膝关节置换术在2至5年的早期高失败率在长期内并未持续存在。尽管胫骨近端内侧代谢变化似乎持续存在,但不一定有症状。BMI > 30和年龄 < 65岁是翻修的重要风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de99/5904245/ff009fe56065/402_2018_2908_Fig1_HTML.jpg

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