Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Public Health Virology Laboratory, Public and Environmental Health, Forensic and Scientific Services, Health Support Queensland, Department of Health, Queensland, Australia.
J Med Virol. 2018 Jun;90(6):1168-1171. doi: 10.1002/jmv.25063. Epub 2018 Mar 13.
In Victoria, Australia, 160 gastroenteritis outbreaks were norovirus positive for the period January-September 2017. A distinctive peak in norovirus outbreaks was seen May-August, with 118 positive outbreaks occurring in the peak period. The peak was primarily due to the emergence of a GII.P4_NewOrleans_2009/GII.4_Sydney_2012 recombinant that had genetically changed sufficiently to escape herd immunity. This recombinant was also identified elsewhere in Australia, with highly similar sequences identified in Queensland during the same time period. The recombinant GII.P4_NewOrleans_2009/GII.4_Sydney_2012 has not been reported to cause norovirus epidemics outside Australia, suggesting regional factors play a role in determining norovirus genotype incidence.
在澳大利亚维多利亚州，2017 年 1 月至 9 月期间有 160 起肠胃炎暴发与诺如病毒阳性有关。2017 年 5 月至 8 月期间诺如病毒暴发呈独特高峰，高峰期有 118 起阳性暴发。这一高峰主要是由于一种 GII.P4_NewOrleans_2009/GII.4_Sydney_2012 重组病毒的出现，这种病毒在遗传上发生了足够的变化，从而逃脱了群体免疫。这种重组病毒也在澳大利亚其他地方被发现，在同一时期昆士兰州也发现了高度相似的序列。这种 GII.P4_NewOrleans_2009/GII.4_Sydney_2012 重组病毒尚未在澳大利亚以外地区引发诺如病毒流行，这表明地区因素在决定诺如病毒基因型发病中起作用。
