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患者自述的药物过敏是否与髋关节镜术前髋关节预后评分较差相关?

Are Self-Reported Medication Allergies Associated With Worse Hip Outcome Scores Prior to Hip Arthroscopy?

机构信息

Houston Methodist Orthopedic and Sports Medicine, Houston, Texas, U.S.A.

Houston Methodist Orthopedic and Sports Medicine, Houston, Texas, U.S.A..

出版信息

Arthroscopy. 2018 Jun;34(6):1856-1861. doi: 10.1016/j.arthro.2018.01.025. Epub 2018 Feb 21.

DOI:10.1016/j.arthro.2018.01.025
PMID:29477606
Abstract

PURPOSE

To determine if there are significant differences in preoperative patient-reported outcome (PRO) scores in patients with and without self-reported medication allergies undergoing hip arthroscopy.

METHODS

Consecutive subjects undergoing hip arthroscopy for femoroacetabular impingement (FAI) syndrome by a single surgeon were retrospectively reviewed. PROs were collected within 6 weeks of the date of surgery. PROs included International Hip Outcome Tool (iHOT-12), Hip Outcome Score (HOS), and Short-Form (SF-12) scores. Allergies to medications were self-reported preoperatively within 6 weeks of the date of surgery. Patient demographics were recorded. Bivariate correlations and multivariate regression models were calculated to identify associations with baseline hip outcome scores.

RESULTS

Two hundred twelve subjects were analyzed (56% female, mean age 35.1 ± 13.2 years). Seventy-two subjects (34%) self-reported allergies (range 1-10; 41 subjects had 1 allergy; 14 subjects had 2; 8 subjects had 3; 2 subjects had 4; 7 subjects had 5 or more). The most commonly reported allergies included penicillin (18), sulfa (13), and codeine (11). Female gender was significantly correlated with number of allergies (Pearson correlation coefficient, 0.188; P < .001). SF-12 Mental Component Score (MCS) was significantly correlated with HOS-ADL (Pearson correlation coefficient, 0.389; P < .001), HOS-SSS (Pearson correlation coefficient, 0.251; P < .001), and iHOT-12 (Pearson correlation coefficient, 0.385; P < .001). There was no significant correlation between number of allergies and all hip PROs. In all multivariate models, the SF-12 MCS had the strongest association with HOS-ADL, HOS-SSS, and iHOT-12 (P < .001 for all). Allergies were not significantly associated with any hip PROs.

CONCLUSIONS

In patients undergoing hip arthroscopy for FAI syndrome, self-reported medication allergies are not significantly associated with preoperative patient-reported hip outcome scores.

LEVEL OF EVIDENCE

Level III, retrospective comparative case series.

摘要

目的

确定接受髋关节镜检查的自述有药物过敏和无药物过敏的患者之间,术前患者报告的结局(PRO)评分是否存在显著差异。

方法

对单名外科医生行髋关节镜检查治疗股骨髋臼撞击综合征(FAI)的连续患者进行回顾性研究。在手术日期后 6 周内收集 PRO。PRO 包括国际髋关节结果工具(iHOT-12)、髋关节结果评分(HOS)和简短形式(SF-12)评分。在手术日期后 6 周内术前自我报告药物过敏。记录患者人口统计学资料。进行双变量相关性和多变量回归模型分析,以确定与基线髋关节结局评分的关联。

结果

分析了 212 名患者(56%为女性,平均年龄 35.1±13.2 岁)。72 名患者(34%)自述有过敏(范围 1-10;41 名患者有 1 种过敏;14 名患者有 2 种;8 名患者有 3 种;2 名患者有 4 种;7 名患者有 5 种或更多)。最常见的过敏反应包括青霉素(18 例)、磺胺(13 例)和可待因(11 例)。女性性别与过敏数量呈显著正相关(皮尔逊相关系数,0.188;P<.001)。SF-12 心理成分评分(MCS)与 HOS-ADL(皮尔逊相关系数,0.389;P<.001)、HOS-SSS(皮尔逊相关系数,0.251;P<.001)和 iHOT-12(皮尔逊相关系数,0.385;P<.001)显著相关。过敏数量与所有髋关节 PRO 之间无显著相关性。在所有多元模型中,SF-12 MCS 与 HOS-ADL、HOS-SSS 和 iHOT-12 具有最强的关联(均 P<.001)。过敏与任何髋关节 PRO 均无显著相关性。

结论

在接受髋关节镜检查治疗 FAI 综合征的患者中,自述药物过敏与术前患者报告的髋关节结局评分无显著相关性。

证据水平

III 级,回顾性比较病例系列。

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