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下背痛疾病:腰椎融合术?

Low back pain disorders: lumbar fusion?

作者信息

Sypert G W

出版信息

Clin Neurosurg. 1986;33:457-83.

PMID:2947771
Abstract

The role of lumbar spine arthrodesis in the treatment of low back pain disorders remains a highly disputed and controversial subject. There are no clear-cut indications for lumbar spine fusion in lumbar degenerative disc disease. In fact, lumbosacral fusion when added to appropriate decompressive surgery has failed on careful statistical analysis to significantly improve the results over decompressive surgery alone. Moreover, in several large series in the literature of lumbosacral fusion in conjunction with discectomy, the results in patients who developed a pseudoarthrosis did as well as matched cases who obtained an excellent arthrodesis. These results should not be surprising since there does not appear to exist a generally accepted operational definition of mechanical (lumbar instability) pain. The author, however, is of the opinion that lumbosacral arthrodesis will prove to have a definite, albeit small, role in the management of the intractable and incapacitating low back pain disorders. This is based on personal clinical experience and the belief that the phenomenon of intractable and incapacitating mechanical low back pain syndromes do exist. Carefully performed prospective clinical studies are requisite to define the mechanical low back pain syndrome and the role of lumbar arthrodesis in the treatment of the low back pain disorders. Given our present limitations, the author suggests that lumbosacral arthrodesis be reserved for patients suffering spondylotic low back pain syndromes who have the following characteristics: intractable and disabling pain; primary complaint of segmental mechanical pain; radiologic evidence consistent with "instability"; minimal or no segmental disease above proposed site of arthrodesis; and minimal or absent psychosocial-economic pain.

摘要

腰椎融合术在治疗下腰痛疾病中的作用仍然是一个备受争议且颇具争议的话题。在腰椎退行性椎间盘疾病中,腰椎融合术并没有明确的适应证。事实上,经过仔细的统计分析,在适当的减压手术基础上增加腰骶融合术,并没有显著改善治疗效果,并不优于单纯的减压手术。此外,在文献中关于腰骶融合术联合椎间盘切除术的几个大型系列研究中,出现假关节的患者的治疗结果与获得良好融合的匹配病例相当。这些结果并不令人惊讶,因为目前似乎不存在一个被普遍接受的机械性(腰椎不稳)疼痛的手术定义。然而,作者认为,腰骶融合术在治疗顽固性和致残性下腰痛疾病中将会证明具有一定的作用,尽管作用较小。这是基于个人临床经验以及坚信确实存在顽固性和致残性机械性下腰痛综合征这一信念。需要进行精心设计的前瞻性临床研究来明确机械性下腰痛综合征以及腰椎融合术在治疗下腰痛疾病中的作用。鉴于我们目前的局限性,作者建议腰骶融合术应保留给患有以下特征的退变性下腰痛综合征患者:顽固性和致残性疼痛;节段性机械性疼痛为主诉;影像学证据与“不稳”相符;拟融合部位上方节段性病变轻微或无病变;以及心理社会经济因素导致的疼痛轻微或不存在。

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