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单纯使用 Trabecular Metal 椎间融合笼行后路腰椎间融合术治疗复发性腰椎间盘突出症和腰痛

Posterior lumbar interbody fusion with stand-alone Trabecular Metal cages for repeatedly recurrent lumbar disc herniation and back pain.

机构信息

Neurosurgical Center Amsterdam, Neurosurgery Spine Clinic, Sint Lucas Andreas Hospital, and Academic Medical Center, Amsterdam, The Netherlands.

出版信息

J Neurosurg Spine. 2014 Jun;20(6):617-22. doi: 10.3171/2014.2.SPINE13548. Epub 2014 Mar 28.

Abstract

OBJECT

Patients with recurrent sciatica due to repeated reherniation of the intervertebral disc carry a poor prognosis for recovery and create a large burden on society. There is no consensus about the best treatment for this patient group. The goal of this study was to evaluate the 12-month results of the placement of stand-alone Trabecular Metal cages in these patients.

METHODS

The authors performed a retrospective analysis of 26 patients with recurrent disc herniations treated with stand-alone posterior lumbar interbody fusion (PLIF) with Trabecular Metal cages. At 1 year patients were evaluated using the Roland Morris Disability Questionnaire (RMDQ) and a visual analog scale (VAS) for back and leg pain. Furthermore, Likert scores of perceived recovery and satisfaction with the treatment were recorded. Lumbar spine radiographs after 1 year were compared with postoperative radiographs to measure subsidence. Stability of the operated segment was assessed using dynamic radiography.

RESULTS

The patient group consisted of 26 patients (62% male) with a mean age of 45.7 ± 11.4 years (± SD). Patients had a history of 1 (31%), 2 (42%), or more (27%) discectomies at the same level. The mean follow-up period was 15.3 ± 7.3 months. At follow-up the mean VAS score for pain in the affected leg was 36.7 ± 27.9. The mean VAS score for back pain was 42.5 ± 30.2. The mean RMDQ score at follow-up was 9.8 ± 6.2. Twelve (46%) of the 26 patients had a global perceived good recovery. With respect to treatment satisfaction, 18 patients (69%) were content or very content with the operation and would recommend it. Disc height was increased immediately postoperatively, and at the 1-year follow-up it was still significantly higher compared with the preoperative height (mean 41% ± 38.7%, range -25.7 to 126.8, paired t-test, both p < 0.001), although a mean of 7.52% ± 11.6% subsidence occurred (median 2.0% [interquartile range 0.0%-10.9%], p < 0.003). No significant correlation between subsidence and postoperative back pain was found (Spearman's rho -0.2, p = 0.459). Flexion-extension radiographs showed instability in 1 patient.

CONCLUSIONS

Although only 46% of patients reported a good recovery with significant reductions in back and leg pain, 85% of patients reported at least some benefit from the operation, and a marked improvement in working status at follow-up was noted. In view of previously published poor results of instrumented lumbar fusion for patients with failed back surgery syndrome, the present data indicate that Trabecular Metal interbody fusion cages can be used in a stand-alone fashion and should not always need supplemental posterior fixation in patients with recurrent disc herniation without spinal instability, although a long-term follow-up study is warranted.

摘要

目的

由于椎间盘反复突出导致复发性坐骨神经痛的患者预后恢复较差,给社会带来了巨大负担。对于这组患者,最佳治疗方法尚无共识。本研究旨在评估单独使用 Trabecular Metal 笼在这些患者中的 12 个月结果。

方法

作者对 26 例接受单独后路腰椎体间融合术(PLIF)伴 Trabecular Metal 笼治疗的复发性椎间盘突出症患者进行回顾性分析。术后 1 年,采用 Roland Morris 残疾问卷(RMDQ)和视觉模拟评分(VAS)评估腰痛和腿痛,并记录对恢复情况的感知和对治疗的满意度的 Likert 评分。术后 1 年拍摄腰椎正侧位片,与术后片对比测量下沉量。采用动力位片评估手术节段的稳定性。

结果

患者组包括 26 例(62%为男性)患者,平均年龄为 45.7±11.4 岁(均数±标准差)。患者在同一水平曾接受 1 次(31%)、2 次(42%)或更多次(27%)椎间盘切除术。平均随访时间为 15.3±7.3 个月。随访时,受累下肢 VAS 疼痛评分平均为 36.7±27.9。腰背 VAS 疼痛评分平均为 42.5±30.2。RMDQ 评分平均为 9.8±6.2。26 例患者中 12 例(46%)认为整体恢复良好。在治疗满意度方面,18 例患者(69%)对手术感到满意或非常满意,并会推荐这种手术。术后即刻椎间盘高度增加,术后 1 年仍明显高于术前(平均增加 41%±38.7%,范围-25.7%至 126.8%,配对 t 检验,均 p<0.001),但平均发生 7.52%±11.6%的下沉(中位数为 2.0%[四分位间距 0.0%~10.9%],p<0.003)。未发现下沉与术后腰痛之间存在显著相关性(Spearman 相关系数-0.2,p=0.459)。1 例患者屈伸位片显示不稳定。

结论

尽管只有 46%的患者报告恢复良好,且腰背疼痛明显减轻,但 85%的患者报告至少从手术中受益,且随访时工作状态显著改善。鉴于复发性椎间盘突出症患者后路融合术的不良结果,本研究数据表明,Trabecular Metal 椎间融合器可单独使用,在无脊柱不稳的复发性椎间盘突出症患者中,无需常规行后路附加固定,但仍需长期随访研究。

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