Epstein Danny, Borohovitz Ariel, Merdler Ilan, Furman Moran, Atalli Emmanuel, Sorkin Alex, Stainfeld Yaniv, Isenberg Yoni, Mashiach Tanya, Shapira Shachar, Weisshof Roni, Dann Eldad J
Israeli Medical Corps, Israel Defense Forces, Tel HaShomer, Israel.
Rambam Health Care Campus, Haifa, Israel.
Acta Haematol. 2018;139(3):141-147. doi: 10.1159/000485736. Epub 2018 Feb 23.
The objectives of our study were to determine the effect of strenuous physical training on the prevalence of iron deficiency anemia (IDA), iron deficiency (ID) with normal hemoglobin (Hb), and anemia without ID.
Our study was a prospective observational study. We followed 115 healthy male recruits in the Israel Defense Forces elite units during 15 months of training. Blood samples were collected at recruitment and at 6-, 9- and 15-month follow-ups.
Upon recruitment, anemia (Hb < 14 g/dL), ID, and ID anemia (IDA) were diagnosed in 28, 31, and 9% of individuals, respectively. Sixty-three subjects (54%) were followed for 6 months; 9 of them (14%) developed new-onset IDA. Among them, the prevalence of anemia rose from 19 to 52%, and ID from 33 to 35%. At the 15-month follow-up, 29% had developed new-onset IDA and 65% showed evidence of ID.
We report a high prevalence of anemia, ID, and IDA among young healthy males participating in prolonged strenuous training programs. These findings can be partly explained by the physiological changes associated with strenuous physical activity. Further investigations aiming to develop specific diagnostic guidelines for this unique population are warranted.
我们研究的目的是确定高强度体育训练对缺铁性贫血（IDA）、血红蛋白（Hb）正常的缺铁（ID）以及非ID性贫血患病率的影响。
我们的研究是一项前瞻性观察性研究。我们在15个月的训练期间跟踪了以色列国防军精英部队的115名健康男性新兵。在招募时以及随访的第6、9和15个月采集血样。
招募时，分别有28%、31%和9%的个体被诊断为贫血（Hb<14g/dL）、ID和ID性贫血（IDA）。63名受试者（54%）被随访6个月；其中9人（14%）出现新发IDA。其中，贫血患病率从19%升至52%，ID患病率从33%升至35%。在15个月的随访中，29%的人出现新发IDA，65%的人有ID证据。
我们报告了参与长期高强度训练计划的年轻健康男性中贫血、ID和IDA的高患病率。这些发现部分可以用与剧烈体力活动相关的生理变化来解释。有必要进一步开展研究以制定针对这一独特人群的具体诊断指南。
