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一年级学生缺铁与贫血之间不存在关联

The Lack of Association of Iron Deficiency With Anemia in First Graders.

作者信息

Jaber Lutfi, Diamond Gary

机构信息

*The Bridge to Peace Community Pediatric Center, Taibe †Neurology and Child Development Clinic, Schneider Children's Medical Center of Israel, Petah Tikva ‡Clalit Health Services, Tel Aviv §Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel ∥Rose F. Kennedy Center, CERC, Albert Einstein College of Medicine, Bronx, NY.

出版信息

J Pediatr Hematol Oncol. 2015 Oct;37(7):524-8. doi: 10.1097/MPH.0000000000000423.

Abstract

Iron-deficiency anemia (IDA) is a disease with worldwide prevalence. The prevalence of IDA and iron deficiency (ID) was ascertained by serum ferritin and mean corpuscular volume (MCV) levels in first graders in Taibe. A total of 1132 first graders were tested for the iron status between the years 1999 and 2004. Serum ferritin, hemoglobin (Hb), hematocrit, MCV, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and red and white blood cell counts were checked. Hb<11.5 g/dL, serum ferritin<12 μg/L, and MCV<75 fL were the criteria we chose for establishing IDA, and serum ferritin<12 μg/L and MCV<75 fL for establishing ID. Non-IDA was ascertained by a low Hb value, coupled with normal serum ferritin. The mean value of serum ferritin was 26.6±16.8 μg/L. Eighty-two (11.8%) children had low serum ferritin (<12 μg/L). The mean value of Hb was 12.3±0.8, and 80 (11.5%) of the children had low Hb. A correlation was found between hematological parameters and Hb. The prevalence of IDA, ID, and non-IDA was 2.2%, 11.8%, and 9.4%, respectively. No correlation was found between indices of anemia and demographic characteristics. Non-IDA and ID are prevalent in 5 to 6-year-old Arab children; however, IDA is surprisingly low. We need to look for other causes of anemia in this age group of the population.

摘要

缺铁性贫血(IDA)是一种全球普遍存在的疾病。通过检测台北市一年级学生的血清铁蛋白和平均红细胞体积(MCV)水平来确定IDA和铁缺乏(ID)的患病率。在1999年至2004年期间,共对1132名一年级学生进行了铁状态检测。检测了血清铁蛋白、血红蛋白(Hb)、血细胞比容、MCV、平均红细胞血红蛋白、平均红细胞血红蛋白浓度以及红细胞和白细胞计数。我们选择Hb<11.5 g/dL、血清铁蛋白<12 μg/L和MCV<75 fL作为诊断IDA的标准,血清铁蛋白<12 μg/L和MCV<75 fL作为诊断ID的标准。非IDA通过低Hb值且血清铁蛋白正常来确定。血清铁蛋白的平均值为26.6±16.8 μg/L。82名(11.8%)儿童血清铁蛋白水平低(<12 μg/L)。Hb的平均值为12.3±0.8,80名(11.5%)儿童Hb水平低。发现血液学参数与Hb之间存在相关性。IDA、ID和非IDA的患病率分别为2.2%、11.8%和9.4%。未发现贫血指标与人口统计学特征之间存在相关性。非IDA和ID在5至6岁的阿拉伯儿童中普遍存在;然而,IDA的患病率出奇地低。我们需要在这个年龄段的人群中寻找贫血的其他原因。

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